Literature DB >> 25130941

COSAN as a molecular imaging platform: synthesis and "in vivo" imaging.

Kiran B Gona1, Adnana Zaulet, Vanessa Gómez-Vallejo, Francesc Teixidor, Jordi Llop, Clara Viñas.   

Abstract

A labelling method for the covalent attachment of radioiodine to the boron-rich 8-I-cobaltabisdicarbollide (I-COSAN) and a bi-functional (iodine and PEG) COSAN derivative, [3,3'-Co(8-I-1,2-C2B9H10)(8'-(OCH2CH2)2COOC6H5-1',2'-C2B9H10)], is reported. Biodistribution studies in rodents using dissection/gamma counting and in vivo nuclear imaging have been performed. The general strategy reported here can be applied in the future to COSAN derivatives bearing a wide range of functionalities.

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Year:  2014        PMID： 25130941     DOI： 10.1039/c4cc05058d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Biological interaction of living cells with COSAN-based synthetic vesicles.

Authors:  Màrius Tarrés; Elisabetta Canetta; Eleanor Paul; Jordan Forbes; Karima Azzouni; Clara Viñas; Francesc Teixidor; Adrian J Harwood
Journal:  Sci Rep       Date:  2015-01-15       Impact factor: 4.379

2.  Gold Nanoparticles as Boron Carriers for Boron Neutron Capture Therapy: Synthesis, Radiolabelling and In vivo Evaluation.

Authors:  Krishna R Pulagam; Kiran B Gona; Vanessa Gómez-Vallejo; Jan Meijer; Carolin Zilberfain; Irina Estrela-Lopis; Zuriñe Baz; Unai Cossío; Jordi Llop
Journal:  Molecules       Date:  2019-10-07       Impact factor: 4.411

3.  Interactions of Boron Clusters and their Derivatives with Serum Albumin.

Authors:  Tomasz M Goszczyński; Krzysztof Fink; Konrad Kowalski; Zbigniew J Leśnikowski; Janusz Boratyński
Journal:  Sci Rep       Date:  2017-08-29       Impact factor: 4.379

4.  2,2'-Bipyridine-Modified Tamoxifen: A Versatile Vector for Molybdacarboranes.

Authors:  Benedikt Schwarze; Sanja Jelača; Linda Welcke; Danijela Maksimović-Ivanić; Sanja Mijatović; Evamarie Hey-Hawkins
Journal:  ChemMedChem       Date:  2019-11-18       Impact factor: 3.466

5.  Cobaltabis(dicarbollide) ([o-COSAN]-) as Multifunctional Chemotherapeutics: A Prospective Application in Boron Neutron Capture Therapy (BNCT) for Glioblastoma.

Authors:  Miquel Nuez-Martinez; Catarina I G Pinto; Joana F Guerreiro; Filipa Mendes; Fernanda Marques; Amanda Muñoz-Juan; Jewel Ann Maria Xavier; Anna Laromaine; Valeria Bitonto; Nicoletta Protti; Simonetta Geninatti Crich; Francesc Teixidor; Clara Viñas
Journal:  Cancers (Basel)       Date:  2021-12-19       Impact factor: 6.639

6.  Electrochemistry of Cobalta Bis(dicarbollide) Ions Substituted at Carbon Atoms with Hydrophilic Alkylhydroxy and Carboxy Groups.

Authors:  Lukáš Fojt; Bohumír Grüner; Jan Nekvinda; Ece Zeynep Tűzűn; Luděk Havran; Miroslav Fojta
Journal:  Molecules       Date:  2022-03-08       Impact factor: 4.411
  6 in total

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