G S Renukananda1, Santosh U P2, Nitha Mary George3. 1. Professor & Unit Chief, Department of Otorhinolaryngology, J.J.M. Medical College, Davangere , Karnataka, India . 2. Professor, Department of Otorhinolaryngology, J.J.M. Medical College, Davangere , Karnataka, India . 3. Postgraduate, Department of Otorhinolaryngology, J.J.M. Medical College, Davangere , Karnataka, India .
Abstract
OBJECTIVES: To study the microbial flora and determine the efficacy of topical ciprofloxacin ear drops in comparison with combination of topical and oral ciprofloxacin as first line management in patients diagnosed with chronic suppurative otitis media. MATERIALS AND METHODS: Prospective randomized interventional clinical trial on 100 patients who presented with an acute episode of CSOM to our outpatient department. RESULTS: In our study, topical ciprofloxacin therapy was found to be an effective treatment for an acute on chronic otitis media as was the combination therapy though the overall recurrence rate was found to be more in the former group. CONCLUSION: In the absence of systemic infection or serious underlying disease, topical antibiotics alone constitute first line treatment for most patients with chronic suppurative otitis media, finding no evidence that systemic antibiotics alone or in combination with topical preparations improve treatment outcomes compared with topical antibiotics alone.
RCT Entities:
OBJECTIVES: To study the microbial flora and determine the efficacy of topical ciprofloxacin ear drops in comparison with combination of topical and oral ciprofloxacin as first line management in patients diagnosed with chronic suppurative otitis media. MATERIALS AND METHODS: Prospective randomized interventional clinical trial on 100 patients who presented with an acute episode of CSOM to our outpatient department. RESULTS: In our study, topical ciprofloxacin therapy was found to be an effective treatment for an acute on chronic otitis media as was the combination therapy though the overall recurrence rate was found to be more in the former group. CONCLUSION: In the absence of systemic infection or serious underlying disease, topical antibiotics alone constitute first line treatment for most patients with chronic suppurative otitis media, finding no evidence that systemic antibiotics alone or in combination with topical preparations improve treatment outcomes compared with topical antibiotics alone.
Authors: J E Dohar; C M Alper; E A Rose; W J Doyle; M L Casselbrant; M A Kenna; C D Bluestone Journal: Ann Otol Rhinol Laryngol Date: 1998-10 Impact factor: 1.547
Authors: Guillermo L Monroy; Paritosh Pande; Ryan M Nolan; Ryan L Shelton; Ryan G Porter; Michael A Novak; Darold R Spillman; Eric J Chaney; Daniel T McCormick; Stephen A Boppart Journal: J Biomed Opt Date: 2017-12 Impact factor: 3.170
Authors: Lee-Yee Chong; Karen Head; Katie E Webster; Jessica Dew; Peter Richmond; Tom Snelling; Mahmood F Bhutta; Anne Gm Schilder; Martin J Burton; Christopher G Brennan-Jones Journal: Cochrane Database Syst Rev Date: 2021-02-04
Authors: Ayman A Elshayeb; Abdelazim A Ahmed; Marmar A El Siddig; Adil A El Hussien Journal: Ann Clin Microbiol Antimicrob Date: 2017-11-14 Impact factor: 3.944
Authors: Lee-Yee Chong; Karen Head; Katie E Webster; Jessica Daw; Peter Richmond; Tom Snelling; Mahmood F Bhutta; Anne Gm Schilder; Martin J Burton; Christopher G Brennan-Jones Journal: Cochrane Database Syst Rev Date: 2021-02-09
Authors: Christopher G Brennan-Jones; Karen Head; Lee-Yee Chong; Martin J Burton; Anne Gm Schilder; Mahmood F Bhutta Journal: Cochrane Database Syst Rev Date: 2020-01-02
Authors: Karen Head; Lee-Yee Chong; Mahmood F Bhutta; Peter S Morris; Shyan Vijayasekaran; Martin J Burton; Anne Gm Schilder; Christopher G Brennan-Jones Journal: Cochrane Database Syst Rev Date: 2020-01-06
Authors: Karen Head; Lee-Yee Chong; Mahmood F Bhutta; Peter S Morris; Shyan Vijayasekaran; Martin J Burton; Anne Gm Schilder; Christopher G Brennan-Jones Journal: Cochrane Database Syst Rev Date: 2020-01-06