Literature DB >> 2511838

Genetics of increased lifespan in Drosophila.

M R Rose.   

Abstract

Natural selection in the laboratory has been used to produce populations of Drosophila with genetically increased lifespan. These populations have been used to determine the physiological basis of postponed ageing and its pleiotropic concomitants. It appears that many loci and a number of physiological alterations are involved in increased lifespan.

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Mesh：

Year:  1989        PMID： 2511838     DOI： 10.1002/bies.950110505

Source DB:  PubMed          Journal:  Bioessays        ISSN： 0265-9247            Impact factor:   4.345


  6 in total

1.  Genetic variation in the Yolk protein expression network of Drosophila melanogaster: sex-biased negative correlations with longevity.

Authors:  A M Tarone; L M McIntyre; L G Harshman; S V Nuzhdin
Journal:  Heredity (Edinb)       Date:  2012-07-04       Impact factor: 3.821

Review 2.  Comparative genetics of longevity and cancer: insights from long-lived rodents.

Authors:  Vera Gorbunova; Andrei Seluanov; Zhengdong Zhang; Vadim N Gladyshev; Jan Vijg
Journal:  Nat Rev Genet       Date:  2014-07-01       Impact factor: 53.242

3.  Should we enhance animals?

Authors:  S Chan
Journal:  J Med Ethics       Date:  2009-11       Impact factor: 2.903

Review 4.  What have two decades of laboratory life-history evolution studies on Drosophila melanogaster taught us?

Authors:  N G Prasad; Amitabh Joshi
Journal:  J Genet       Date:  2003 Apr-Aug       Impact factor: 1.166

5.  Two-dimensional protein electrophoretic analysis of postponed aging in Drosophila.

Authors:  J E Fleming; G S Spicer; R C Garrison; M R Rose
Journal:  Genetica       Date:  1993       Impact factor: 1.082

6.  Nucleotide diversity inflation as a genome-wide response to experimental lifespan extension in Drosophila melanogaster.

Authors:  Pawel Michalak; Lin Kang; Pernille M Sarup; Mads F Schou; Volker Loeschcke
Journal:  BMC Genomics       Date:  2017-01-14       Impact factor: 3.969
  6 in total

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