Literature DB >> 25114400

Blood substitutes: possibilities with nanotechnology.

Feroz Alam1, Neha Yadav2, Murad Ahmad1, Mariyam Shadan1.   

Abstract

Nanotechnology deals with molecules in the nanometer (10(-9)) range and is currently being used successfully in the field of medicine. Nanotechnology has important implications in nearly all the branches of medicine and it has all the capabilities to revolutionize the vast field of medicine in future. Nanotechnological advancements have been used for the preparation of artificial hemoglobin. It is formed by assembling the hemoglobin molecules into a soluble complex. A recent approach includes the assembling of this artificial hemoglobin with enzymes such as catalase and superoxide dismutase into a nano-complex. This complex acts as an oxygen carrier as well as an antioxidant in conditions with ischemia-reperfusion injuries.

Entities:  

Keywords:  Artificial red cells; Blood substitutes; Nanotechnology; Polyhemoglobin

Year:  2013        PMID: 25114400      PMCID: PMC4115085          DOI: 10.1007/s12288-013-0309-5

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN: 0971-4502            Impact factor:   0.900


  23 in total

1.  Mortality and morbidity in patients with very low postoperative Hb levels who decline blood transfusion.

Authors:  Jeffrey L Carson; Helaine Noveck; Jesse A Berlin; Steven A Gould
Journal:  Transfusion       Date:  2002-07       Impact factor: 3.157

2.  SEMIPERMEABLE MICROCAPSULES.

Authors:  T M CHANG
Journal:  Science       Date:  1964-10-23       Impact factor: 47.728

3.  Intracellular organic phosphates as regulators of oxygen release by haemoglobin.

Authors:  R Benesch; R E Benesch
Journal:  Nature       Date:  1969-02-15       Impact factor: 49.962

Review 4.  The potential role of perfluorochemicals (PFCs) in diagnostic imaging.

Authors:  R F Mattrey
Journal:  Artif Cells Blood Substit Immobil Biotechnol       Date:  1994

5.  Erythrocyte substitute for perfusion of brain.

Authors:  H A Sloviter; T Kamimoto
Journal:  Nature       Date:  1967-11-04       Impact factor: 49.962

Review 6.  Perfluorinated blood substitutes and artificial oxygen carriers.

Authors:  K C Lowe
Journal:  Blood Rev       Date:  1999-09       Impact factor: 8.250

7.  Submicron biodegradable polymer membrane hemoglobin nanocapsules as potential blood substitutes: a preliminary report.

Authors:  W P Yu; T M Chang
Journal:  Artif Cells Blood Substit Immobil Biotechnol       Date:  1994

8.  Biodegradable semipermeable microcapsules containing enzymes, hormones, vaccines, and other biologicals.

Authors:  T M Chang
Journal:  J Bioeng       Date:  1976-11

9.  Polyhemoglobin-superoxide dismutase-catalase as a blood substitute with antioxidant properties.

Authors:  F D'Agnillo; T M Chang
Journal:  Nat Biotechnol       Date:  1998-07       Impact factor: 54.908

10.  Polyethylene glycol-modified liposome-encapsulated hemoglobin: a long circulating red cell substitute.

Authors:  W T Phillips; R W Klipper; V D Awasthi; A S Rudolph; R Cliff; V Kwasiborski; B A Goins
Journal:  J Pharmacol Exp Ther       Date:  1999-02       Impact factor: 4.030

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  1 in total

Review 1.  Nanomedicines: A Potential Treatment for Blood Disorder Diseases.

Authors:  Nan Zhang; Ming-Yuan Wei; Qiang Ma
Journal:  Front Bioeng Biotechnol       Date:  2019-11-28
  1 in total

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