Literature DB >> 25111733

Development of an applicator for eye lens dosimetry during radiotherapy.

J M Park1, J Lee, H S Kim, S-J Ye, J-I Kim.   

Abstract

OBJECTIVE: To develop an applicator for in vivo measurements of lens dose during radiotherapy.
METHODS: A contact lens-shaped applicator made of acrylic was developed for in vivo measurements of lens dose. This lens applicator allows the insertion of commercially available metal oxide semiconductor field effect transistors (MOSFETs) dosemeters. CT images of an anthropomorphic phantom with and without the applicator were acquired. Ten volumetric modulated arc therapy plans each for the brain and the head and neck cancer were generated and delivered to an anthropomorphic phantom. The differences between the measured and the calculated doses at the lens applicator, as well as the differences between the measured and the calculated doses at the surface of the eyelid were acquired.
RESULTS: The average difference between the measured and the calculated doses with the applicator was 3.1 ± 1.8 cGy with a micro MOSFET and 2.8 ± 1.3 cGy with a standard MOSFET. The average difference without the lens applicator was 4.8 ± 5.2 cGy with the micro MOSFET and 5.7 ± 6.5 cGy with the standard MOSFET. The maximum difference with the micro MOSFET was 10.5 cGy with the applicator and 21.1 cGy without the applicator. For the standard MOSFET, it was 6.8 cGy with the applicator and 27.6 cGy without the applicator.
CONCLUSION: The lens applicator allowed reduction of the differences between the calculated and the measured doses during in vivo measurement for the lens compared with in vivo measurement at the surface of the eyelid. ADVANCES IN KNOWLEDGE: By using an applicator for in vivo dosimetry of the eye lens, it was possible to reduce the measurement uncertainty.

Entities:  

Mesh:

Year:  2014        PMID: 25111733      PMCID: PMC4170865          DOI: 10.1259/bjr.20140311

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  24 in total

1.  AAPM's TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams.

Authors:  P R Almond; P J Biggs; B M Coursey; W F Hanson; M S Huq; R Nath; D W Rogers
Journal:  Med Phys       Date:  1999-09       Impact factor: 4.071

2.  Investigation of the use of MOSFET for clinical IMRT dosimetric verification.

Authors:  Cynthia F Chuang; Lynn J Verhey; Ping Xia
Journal:  Med Phys       Date:  2002-06       Impact factor: 4.071

Review 3.  Volumetric modulated arc therapy: a review of current literature and clinical use in practice.

Authors:  M Teoh; C H Clark; K Wood; S Whitaker; A Nisbet
Journal:  Br J Radiol       Date:  2011-11       Impact factor: 3.039

4.  Dose conversion coefficients for photon exposure of the human eye lens.

Authors:  R Behrens; G Dietze
Journal:  Phys Med Biol       Date:  2010-12-22       Impact factor: 3.609

5.  Application of commercial MOSFET detectors for in vivo dosimetry in the therapeutic x-ray range from 80 kV to 250 kV.

Authors:  Christian Ehringfeld; Susanne Schmid; Karin Poljanc; Christian Kirisits; Hannes Aiginger; Dietmar Georg
Journal:  Phys Med Biol       Date:  2005-01-21       Impact factor: 3.609

6.  Monte Carlo simulation of MOSFET detectors for high-energy photon beams using the PENELOPE code.

Authors:  Vanessa Panettieri; Maria Amor Duch; Núria Jornet; Mercè Ginjaume; Pablo Carrasco; Andreu Badal; Xavier Ortega; Montserrat Ribas
Journal:  Phys Med Biol       Date:  2006-12-20       Impact factor: 3.609

7.  Real-time in vivo dosimetry with MOSFET detectors in serial tomotherapy for head and neck cancer patients.

Authors:  Zhen-Yu Qi; Xiao-Wu Deng; Shao-Min Huang; Almon Shiu; Michael Lerch; Peter Metcalfe; Anatoly Rosenfeld; Tomas Kron
Journal:  Int J Radiat Oncol Biol Phys       Date:  2011-01-14       Impact factor: 7.038

8.  Evaluation of superficial dosimetry between treatment planning system and measurement for several breast cancer treatment techniques.

Authors:  Yuichi Akino; Indra J Das; Gregory K Bartlett; Hualin Zhang; Elizabeth Thompson; Jennifer E Zook
Journal:  Med Phys       Date:  2013-01       Impact factor: 4.071

9.  TLD extrapolation for skin dose determination in vivo.

Authors:  T Kron; M Butson; F Hunt; J Denham
Journal:  Radiother Oncol       Date:  1996-11       Impact factor: 6.280

10.  Radiation dose to the lens and cataract formation.

Authors:  J M Henk; R A Whitelocke; A P Warrington; E M Bessell
Journal:  Int J Radiat Oncol Biol Phys       Date:  1993-04-02       Impact factor: 7.038

View more
  2 in total

1.  Assessing Human Eye Exposure to UV Light: A Narrative Review.

Authors:  Michele Marro; Laurent Moccozet; David Vernez
Journal:  Front Public Health       Date:  2022-07-06

2.  A Patient-Specific Polylactic Acid Bolus Made by a 3D Printer for Breast Cancer Radiation Therapy.

Authors:  So-Yeon Park; Chang Heon Choi; Jong Min Park; MinSoo Chun; Ji Hye Han; Jung-In Kim
Journal:  PLoS One       Date:  2016-12-08       Impact factor: 3.240

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.