Literature DB >> 25108084

Causes of exercise intolerance in heart failure with preserved ejection fraction: searching for consensus.

Nicholas E Houstis1, Gregory D Lewis2.   

Abstract

Exercise intolerance is one of the cardinal symptoms of heart failure with preserved ejection fraction (HFpEF). We review its mechanistic basis using evidence from exercise studies. One barrier to a consensus understanding of the pathophysiology is heterogeneity of the patient population. Therefore, we pay special attention to varying study definitions of the disease and their possible impact on the causal factors that are implicated. We then discuss the role of exercise testing and its potential to subtype HFpEF in to more homogeneous mechanism-based subclasses.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Exercise testing; Fick; VO(2)max; diagnostic criteria

Mesh：

Year:  2014        PMID： 25108084     DOI： 10.1016/j.cardfail.2014.07.010

Source DB:  PubMed          Journal:  J Card Fail        ISSN： 1071-9164            Impact factor:   5.712


  9 in total

Review 1.  Exercise Intolerance In Heart Failure With Preserved Ejection Fraction.

Authors:  Anisha A Gupte; Dale J Hamilton
Journal:  Methodist Debakey Cardiovasc J       Date:  2016 Apr-Jun

2.  Effect of Spironolactone on Exercise Tolerance and Arterial Function in Older Adults with Heart Failure with Preserved Ejection Fraction.

Authors:  Bharathi Upadhya; William G Hundley; Peter H Brubaker; Timothy M Morgan; Kathryn P Stewart; Dalane W Kitzman
Journal:  J Am Geriatr Soc       Date:  2017-05-19       Impact factor: 5.562

Review 3.  Using exercise to measure and modify cardiac function.

Authors:  Colin Platt; Nicholas Houstis; Anthony Rosenzweig
Journal:  Cell Metab       Date:  2015-02-03       Impact factor: 27.287

Review 4.  Determinants of exercise intolerance in patients with heart failure and reduced or preserved ejection fraction.

Authors:  Mark J Haykowsky; Corey R Tomczak; Jessica M Scott; D Ian Paterson; Dalane W Kitzman
Journal:  J Appl Physiol (1985)       Date:  2015-04-24

Review 5.  The Nitrate-Nitrite-NO Pathway and Its Implications for Heart Failure and Preserved Ejection Fraction.

Authors:  Julio A Chirinos; Payman Zamani
Journal:  Curr Heart Fail Rep       Date:  2016-02

6.  Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: Diagnosing and Ranking Its Causes Using Personalized O2 Pathway Analysis.

Authors:  Nicholas E Houstis; Aaron S Eisman; Paul P Pappagianopoulos; Luke Wooster; Cole S Bailey; Peter D Wagner; Gregory D Lewis
Journal:  Circulation       Date:  2017-10-09       Impact factor: 29.690

7.  CXCR4 Antagonism Reduces Cardiac Fibrosis and Improves Cardiac Performance in Dilated Cardiomyopathy.

Authors:  Po-Yin Chu; Mandar S Joshi; Duncan Horlock; Helen Kiriazis; David M Kaye
Journal:  Front Pharmacol       Date:  2019-02-19       Impact factor: 5.810

8.  Comprehensive Physiological Modeling Provides Novel Insights Into Heart Failure With Preserved Ejection Fraction Physiology.

Authors:  David M Kaye; Emil Wolsk; Shane Nanayakkara; Justin Mariani; Christian Hassager; Finn Gustafsson; Jacob E Moller; Kenji Sunagawa; Daniel Burkhoff
Journal:  J Am Heart Assoc       Date:  2021-09-25       Impact factor: 5.501

9.  Combined use of stress echocardiography and cardiopulmonary exercise testing to assess exercise intolerance in patients treated for acute myocardial infarction.

Authors:  Krzysztof Smarz; Tomasz Jaxa-Chamiec; Beata Zaborska; Maciej Tysarowski; Andrzej Budaj
Journal:  PLoS One       Date:  2021-08-05       Impact factor: 3.240
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.