Literature DB >> 25105572

Out of the F-box: reawakening the pancreas.

Bryce A Seifert1, Yue Xiong2.   

Abstract

The adult pancreas lacks stem cells, and consequently, differentiation of pancreatic endocrine cells has been restricted to embryonic development or experimental manipulation. In this issue of Cell Stem Cell, Sancho et al. (2014) show that pancreas-specific loss of the ubiquitin ligase Fbxw7 stabilizes an endocrine-specific transcription factor, Ngn3, thus inducing in vivo β cell neogenesis.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 25105572      PMCID： PMC4172310          DOI： 10.1016/j.stem.2014.07.006

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  10 in total

Review 1.  Mechanisms underlying ubiquitination.

Authors:  C M Pickart
Journal:  Annu Rev Biochem       Date:  2001       Impact factor: 23.643

Review 2.  Pancreatic organogenesis--developmental mechanisms and implications for therapy.

Authors:  Helena Edlund
Journal:  Nat Rev Genet       Date:  2002-07       Impact factor: 53.242

3.  Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation.

Authors:  Yuval Dor; Juliana Brown; Olga I Martinez; Douglas A Melton
Journal:  Nature       Date:  2004-05-06       Impact factor: 49.962

Review 4.  Neurogenin3: a master regulator of pancreatic islet differentiation and regeneration.

Authors:  J Michael Rukstalis; Joel F Habener
Journal:  Islets       Date:  2009 Nov-Dec       Impact factor: 2.694

5.  Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth.

Authors:  Akari Inada; Cameron Nienaber; Hitoshi Katsuta; Yoshio Fujitani; Jared Levine; Rina Morita; Arun Sharma; Susan Bonner-Weir
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-03       Impact factor: 11.205

Review 6.  How to make a functional β-cell.

Authors:  Felicia W Pagliuca; Douglas A Melton
Journal:  Development       Date:  2013-06       Impact factor: 6.868

Review 7.  FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation.

Authors:  Markus Welcker; Bruce E Clurman
Journal:  Nat Rev Cancer       Date:  2008-02       Impact factor: 60.716

8.  How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited.

Authors:  Mark A Atkinson; Jeffrey A Bluestone; George S Eisenbarth; Matthias Hebrok; Kevan C Herold; Domenico Accili; Massimo Pietropaolo; Peter R Arvan; Matthias Von Herrath; Dorene S Markel; Christopher J Rhodes
Journal:  Diabetes       Date:  2011-05       Impact factor: 9.461

9.  In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.

Authors:  Qiao Zhou; Juliana Brown; Andrew Kanarek; Jayaraj Rajagopal; Douglas A Melton
Journal:  Nature       Date:  2008-08-27       Impact factor: 49.962

10.  Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells.

Authors:  Rocio Sancho; Ralph Gruber; Guoqiang Gu; Axel Behrens
Journal:  Cell Stem Cell       Date:  2014-08-07       Impact factor: 24.633
  10 in total
  2 in total

1.  Progenitor cell niches in the human pancreatic duct system and associated pancreatic duct glands: an anatomical and immunophenotyping study.

Authors:  Guido Carpino; Anastasia Renzi; Vincenzo Cardinale; Antonio Franchitto; Paolo Onori; Diletta Overi; Massimo Rossi; Pasquale Bartolomeo Berloco; Domenico Alvaro; Lola M Reid; Eugenio Gaudio
Journal:  J Anat       Date:  2015-11-27       Impact factor: 2.610

2.  Role of TGF-β/Smad Pathway in the Transcription of Pancreas-Specific Genes During Beta Cell Differentiation.

Authors:  Yuhua Gao; Ranxi Zhang; Shanshan Dai; Xue Zhang; Xiangchen Li; Chunyu Bai
Journal:  Front Cell Dev Biol       Date:  2019-12-20
  2 in total

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