Literature DB >> 25105212

Synthesis of functionalized β-lactams and pyrrolidine-2,5-diones through a metal-free sequential Ugi-4CR/cyclization reaction.

Elmira Ghabraie1, Saeed Balalaie, Saber Mehrparvar, Frank Rominger.   

Abstract

An efficient approach for the synthesis of functionalized β-lactams and pyrrolidine-2,5-diones was achieved through a sequential Ugi-4CR/cyclization reaction. Diversity-oriented synthesis, good to high yields, easy workup, and short reaction times are advantages of this procedure.

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Year:  2014        PMID: 25105212     DOI: 10.1021/jo5010422

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  4 in total

Review 1.  The status of isocyanide-based multi-component reactions in Iran (2010-2018).

Authors:  Ronak Afshari; Seyyed Emad Hooshmand; Mohammad Taghi Nazeri; Siamak Javanbakht; Ahmad Shaabani; Reza Mohammadian
Journal:  Mol Divers       Date:  2020-02-18       Impact factor: 2.943

2.  Diastereoselective Synthesis of β-Lactams by Ligand-Controlled Stereodivergent Intramolecular Tsuji-Trost Allylation.

Authors:  Matteo Faltracco; Verena Sukowski; Max van Druenen; Trevor A Hamlin; F Matthias Bickelhaupt; Eelco Ruijter
Journal:  J Org Chem       Date:  2020-07-13       Impact factor: 4.354

3.  New tricks of well-known aminoazoles in isocyanide-based multicomponent reactions and antibacterial activity of the compounds synthesized.

Authors:  Maryna V Murlykina; Maryna N Kornet; Sergey M Desenko; Svetlana V Shishkina; Oleg V Shishkin; Aleksander A Brazhko; Vladimir I Musatov; Erik V Van der Eycken; Valentin A Chebanov
Journal:  Beilstein J Org Chem       Date:  2017-05-31       Impact factor: 2.883

4.  Facile synthesis and biological evaluation of tryptamine-piperazine-2,5-dione conjugates as anticancer agents.

Authors:  Jiang-Ping Meng; Shi-Qiang Li; Yan Tang; Zhi-Gang Xu; Zhong-Zhu Chen; Li-Xia Gao
Journal:  RSC Adv       Date:  2021-08-17       Impact factor: 4.036

  4 in total

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