Literature DB >> 25093746

Maternal microchimerism: friend or foe in type 1 diabetes?

Jody Ye1, Marta Vives-Pi2, Kathleen M Gillespie1.   

Abstract

Increased levels of non-inherited maternal HLA alleles have been detected in the periphery of children with type 1 diabetes and an increased frequency of maternal cells have been identified in type 1 diabetes pancreas. It is now clear that the phenotype of these cells is pancreatic, supporting the hypothesis that maternal cells in human pancreas are derived from multipotent maternal progenitors. Here we hypothesize how increased levels of maternal cells could play a role in islet autoimmunity.

Entities:  

Keywords:  maternal microchimerism; type 1 diabetes

Mesh：

Substances：

Year:  2014        PMID： 25093746      PMCID： PMC4199804          DOI： 10.4161/chim.29870

Source DB:  PubMed          Journal:  Chimerism        ISSN： 1938-1964


  28 in total

1.  Cross-talk of alloimmune response and autoimmunity: role in pathogenesis of chronic rejection.

Authors:  Venkataswarup Tiriveedhi; Joseph Weber; Anil Seetharam; Thalachallour Mohanakumar
Journal:  Discov Med       Date:  2010-03       Impact factor: 2.970

2.  Microchimerism of maternal origin persists into adult life.

Authors:  S Maloney; A Smith; D E Furst; D Myerson; K Rupert; P C Evans; J L Nelson
Journal:  J Clin Invest       Date:  1999-07       Impact factor: 14.808

3.  Specific maternal microchimeric T cells targeting fetal antigens in β cells predispose to auto-immune diabetes in the child.

Authors:  Edwige Roy; Michele Leduc; Sarah Guegan; Latif Rachdi; Nicolas Kluger; Raphael Scharfmann; Selim Aractingi; Kiarash Khosrotehrani
Journal:  J Autoimmun       Date:  2011-03-17       Impact factor: 7.094

Review 4.  Genetic, environmental and stochastic factors in monozygotic twin discordance with a focus on epigenetic differences.

Authors:  Witold Czyz; Julia M Morahan; George C Ebers; Sreeram V Ramagopalan
Journal:  BMC Med       Date:  2012-08-17       Impact factor: 8.775

5.  Early infant feeding and risk of developing type 1 diabetes-associated autoantibodies.

Authors:  Anette-G Ziegler; Sandra Schmid; Doris Huber; Michael Hummel; Ezio Bonifacio
Journal:  JAMA       Date:  2003-10-01       Impact factor: 56.272

6.  Microchimerism is strongly correlated with tolerance to noninherited maternal antigens in mice.

Authors:  Partha Dutta; Melanie Molitor-Dart; Joseph L Bobadilla; Drew A Roenneburg; Zhen Yan; Jose R Torrealba; William J Burlingham
Journal:  Blood       Date:  2009-08-21       Impact factor: 22.113

7.  Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans.

Authors:  Juris J Meier; Alexandra E Butler; Yoshifumi Saisho; Travis Monchamp; Ryan Galasso; Anil Bhushan; Robert A Rizza; Peter C Butler
Journal:  Diabetes       Date:  2008-03-11       Impact factor: 9.461

8.  Hydrolyzed infant formula and early β-cell autoimmunity: a randomized clinical trial.

Authors:  Mikael Knip; Hans K Åkerblom; Dorothy Becker; Hans-Michael Dosch; John Dupre; William Fraser; Neville Howard; Jorma Ilonen; Jeffrey P Krischer; Olga Kordonouri; Margaret L Lawson; Jerry P Palmer; Erkki Savilahti; Outi Vaarala; Suvi M Virtanen
Journal:  JAMA       Date:  2014-06-11       Impact factor: 56.272

9.  Why are levels of maternal microchimerism higher in type 1 diabetes pancreas?

Authors:  Berendine Vanzyl; Raquel Planas; Yi Ye; Alan Foulis; Ronald R de Krijger; Marta Vives-Pi; Kathleen M Gillespie
Journal:  Chimerism       Date:  2010-10

10.  Maternal microchimerism: increased in the insulin positive compartment of type 1 diabetes pancreas but not in infiltrating immune cells or replicating islet cells.

Authors:  Jody Ye; Marta Vives-Pi; Kathleen M Gillespie
Journal:  PLoS One       Date:  2014-01-31       Impact factor: 3.240
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  1 in total

Review 1.  How pregnancy can affect autoimmune diseases progression?

Authors:  Marie-Pierre Piccinni; Letizia Lombardelli; Federica Logiodice; Ornela Kullolli; Paola Parronchi; Sergio Romagnani
Journal:  Clin Mol Allergy       Date:  2016-09-15
  1 in total

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