Literature DB >> 20350490

Cross-talk of alloimmune response and autoimmunity: role in pathogenesis of chronic rejection.

Venkataswarup Tiriveedhi1, Joseph Weber, Anil Seetharam, Thalachallour Mohanakumar.   

Abstract

Chronic rejection following organ transplantation continues to be a major problem in the long-term survival of the engraftment. Recent literature points to role of both the humoral and cellular alloimmune responses in the pathogenesis of chronic rejection. Our recent studies have provided evidence for alloimmune-response-induced de novo development of immune responses to self-antigens in the post-transplant period in the pathogenesis of chronic rejection following lung, heart, and kidney transplantation. This review details our current understanding of two distinct yet inter-dependent immune processes in the immunopathogenesis of chronic rejection.

Mesh：

Substances：

Year:  2010        PMID： 20350490

Source DB:  PubMed          Journal:  Discov Med        ISSN： 1539-6509            Impact factor:   2.970


  12 in total

1.  Inhibition of renin angiotensin aldosterone system causes abrogation of obliterative airways disease through inhibition of tumor necrosis factor-α-dependant interleukin-17.

Authors:  Joseph Weber; Venkataswarup Tiriveedhi; Masashi Takenaka; Wei Lu; Ramsey Hachem; Elbert Trulock; G Alec Patterson; T Mohanakumar
Journal:  J Heart Lung Transplant       Date:  2012-01-29       Impact factor: 10.247

2.  T regulatory cells play a significant role in modulating MHC class I antibody-induced obliterative airway disease.

Authors:  V Tiriveedhi; M Takenaka; S Ramachandran; A E Gelman; V Subramanian; G A Patterson; T Mohanakumar
Journal:  Am J Transplant       Date:  2012-07-23       Impact factor: 8.086

3.  De novo-developed antibodies to donor MHC antigens lead to dysregulation of microRNAs and induction of MHC class II.

Authors:  Zhongping Xu; Deepak K Nayak; Nicholas Benshoff; Ramsey Hachem; Andrew E Gelman; Thalachallour Mohanakumar
Journal:  J Immunol       Date:  2015-05-04       Impact factor: 5.422

4.  A shift in the collagen V antigenic epitope leads to T helper phenotype switch and immune response to self-antigen leading to chronic lung allograft rejection.

Authors:  V Tiriveedhi; N Angaswamy; D Brand; J Weber; A G Gelman; R Hachem; E P Trulock; B Meyers; G Patterson; T Mohanakumar
Journal:  Clin Exp Immunol       Date:  2012-01       Impact factor: 4.330

Review 5.  Alloimmunity and autoimmunity in chronic rejection.

Authors:  Anil Seetharam; Venkataswarup Tiriveedhi; T Mohanakumar
Journal:  Curr Opin Organ Transplant       Date:  2010-08       Impact factor: 2.640

6.  Lipid raft facilitated ligation of K-alpha1-tubulin by specific antibodies on epithelial cells: Role in pathogenesis of chronic rejection following human lung transplantation.

Authors:  Venkataswarup Tiriveedhi; Nataraju Angaswamy; Joseph Weber; T Mohanakumar
Journal:  Biochem Biophys Res Commun       Date:  2010-07-30       Impact factor: 3.575

7.  A role for antibodies to human leukocyte antigens, collagen-V, and K-α1-Tubulin in antibody-mediated rejection and cardiac allograft vasculopathy.

Authors:  Dilip S Nath; Venkataswarup Tiriveedhi; Haseeb Ilias Basha; Donna Phelan; Nader Moazami; Gregory A Ewald; Thalachallour Mohanakumar
Journal:  Transplantation       Date:  2011-05-15       Impact factor: 4.939

Review 8.  Role of antibodies to self-antigens in chronic allograft rejection: potential mechanism and therapeutic implications.

Authors:  Nayan J Sarma; Venkataswarup Tiriveedhi; Nataraju Angaswamy; T Mohanakumar
Journal:  Hum Immunol       Date:  2012-07-10       Impact factor: 2.850

Review 9.  An important role for autoimmunity in the immunopathogenesis of chronic allograft rejection.

Authors:  V Tiriveedhi; N Sarma; T Mohanakumar
Journal:  Int J Immunogenet       Date:  2012-04-10       Impact factor: 1.466

10.  Anti-major histocompatibility complex-induced obliterative airway disease: selective role for CD4 and CD8 T cells in inducing immune responses to self-antigens.

Authors:  Venkataswarup Tiriveedhi; Masashi Takenaka; Nayan J Sarma; Andrew G Gelman; Thalachallour Mohanakumar
Journal:  J Heart Lung Transplant       Date:  2013-05-02       Impact factor: 10.247
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.