Literature DB >> 2509345

Bactericidal power of neutrophils in protein calorie malnutrition.

K C Nayak, A S Sethi, T D Aggarwal, V S Chadda, K K Kumar.   

Abstract

The present study was undertaken to compare the disturbance in bactericidal power of neutrophils in 25 children having protein caloric malnutrition age and sex matched healthy control subjects. There was a highly significant reduction in the percentage of bacteria killed during incubation in children having PCM as compared to healthy control. A direct relationship existed between total serum proteins and bactericidal activity of neutrophils in children having PCM. The impaired bactericidal power of neutrophils can be attributed to impaired synthesis of lysosomal enzymes, glycolytic activity of neutrophils in children having PCM. The exact mechanisms still remain to be elucidated. Decreased bactericidal activity of neutrophils may be one of the mechanisms responsible for infection.

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Year:  1989        PMID： 2509345     DOI： 10.1007/bf02722303

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN： 0019-5456            Impact factor:   1.967


  9 in total

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Journal:  Lancet       Date:  1971-10-30       Impact factor: 79.321

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Journal:  J Pediatr       Date:  1972-12       Impact factor: 4.406

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  9 in total
  9 in total

Review 1.  Higher versus lower protein intake in formula-fed low birth weight infants.

Authors:  Tanis R Fenton; Shahirose S Premji; Heidi Al-Wassia; Reg S Sauve
Journal:  Cochrane Database Syst Rev       Date:  2014-04-21

Review 2.  Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE).

Authors:  Daniel J Raiten; Fayrouz A Sakr Ashour; A Catharine Ross; Simin N Meydani; Harry D Dawson; Charles B Stephensen; Bernard J Brabin; Parminder S Suchdev; Ben van Ommen
Journal:  J Nutr       Date:  2015-04-01       Impact factor: 4.798

3.  Higher versus lower protein intake in formula-fed low birth weight infants.

Authors:  Tanis R Fenton; Heidi Al-Wassia; Shahirose S Premji; Reg S Sauve
Journal:  Cochrane Database Syst Rev       Date:  2020-06-23

Review 4.  Mechanisms of Kwashiorkor-Associated Immune Suppression: Insights From Human, Mouse, and Pig Studies.

Authors:  Husheem Michael; Joshua O Amimo; Gireesh Rajashekara; Linda J Saif; Anastasia N Vlasova
Journal:  Front Immunol       Date:  2022-05-02       Impact factor: 8.786

Review 5.  Impact of Childhood Malnutrition on Host Defense and Infection.

Authors:  Marwa K Ibrahim; Mara Zambruni; Christopher L Melby; Peter C Melby
Journal:  Clin Microbiol Rev       Date:  2017-10       Impact factor: 26.132

Review 6.  Higher versus lower amino acid intake in parenteral nutrition for newborn infants.

Authors:  David A Osborn; Tim Schindler; Lisa J Jones; John Kh Sinn; Srinivas Bolisetty
Journal:  Cochrane Database Syst Rev       Date:  2018-03-05

Review 7.  Interactions of malnutrition and immune impairment, with specific reference to immunity against parasites.

Authors:  S Hughes; P Kelly
Journal:  Parasite Immunol       Date:  2006-11       Impact factor: 2.280

Review 8.  Current Understanding of Innate Immune Cell Dysfunction in Childhood Undernutrition.

Authors:  Claire D Bourke; Kelsey D J Jones; Andrew J Prendergast
Journal:  Front Immunol       Date:  2019-07-29       Impact factor: 7.561

Review 9.  Infection in the Developing Brain: The Role of Unique Systemic Immune Vulnerabilities.

Authors:  Gabriela Singh; Elizabeth W Tucker; Ursula K Rohlwink
Journal:  Front Neurol       Date:  2022-01-24       Impact factor: 4.003
  9 in total

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