Literature DB >> 25091986

Optimal pig donor selection in islet xenotransplantation: current status and future perspectives.

Hai-tao Zhu1, Liang Yu, Yi Lyu, Bo Wang.   

Abstract

Islet transplantation is an attractive treatment of type 1 diabetes mellitus. Xenotransplantation, using the pig as a donor, offers the possibility of an unlimited supply of islet grafts. Published studies demonstrated that pig islets could function in diabetic primates for a long time (>6 months). However, pig-islet xenotransplantation must overcome the selection of an optimal pig donor to obtain an adequate supply of islets with high-quality, to reduce xeno-antigenicity of islet and prolong xenograft survival, and to translate experimental findings into clinical application. This review discusses the suitable pig donor for islet xenotransplantation in terms of pig age, strain, structure/function of islet, and genetically modified pig.

Entities:  

Keywords:  Donor; Islet; Pig; Xenotransplantation

Mesh：

Year:  2014        PMID： 25091986      PMCID： PMC4129088          DOI： 10.1631/jzus.B1400120

Source DB:  PubMed          Journal:  J Zhejiang Univ Sci B        ISSN： 1673-1581            Impact factor:   3.066


  95 in total

1.  Isolation of adult pig islet. In vitro assessment and xenotransplantation.

Authors:  K Inoue; Y Gu; S Shinohara; M Kogire; M Mitsuo; I Nakai; H Hayashi; K Uchida; S Maetani; Y Ikada
Journal:  Int J Pancreatol       Date:  1992-10

2.  Porcine islet isolation outcome is not affected by the amount and distribution of collagen in the pancreas.

Authors:  Denise E Hilling; Josephine K R A Rijkelijkhuizen; H Annemiek M Töns; Onno T Terpstra; Eelco Bouwman
Journal:  Xenotransplantation       Date:  2010 May-Jun       Impact factor: 3.907

3.  Differentiation and expansion of beta cell mass in porcine neonatal pancreatic cell clusters transplanted into nude mice.

Authors:  K H Yoon; R R Quickel; K Tatarkiewicz; T R Ulrich; J Hollister-Lock; N Trivedi; S Bonner-Weir; G C Weir
Journal:  Cell Transplant       Date:  1999 Nov-Dec       Impact factor: 4.064

4.  Islet xenotransplantation using gal-deficient neonatal donors improves engraftment and function.

Authors:  P Thompson; I R Badell; M Lowe; J Cano; M Song; F Leopardi; J Avila; R Ruhil; E Strobert; G Korbutt; G Rayat; R Rajotte; N Iwakoshi; C P Larsen; A D Kirk
Journal:  Am J Transplant       Date:  2011-08-29       Impact factor: 8.086

5.  Insulin secretion and glucose metabolism in alpha 1,3-galactosyltransferase knock-out pigs compared to wild-type pigs.

Authors:  Anna Casu; Gabriel J Echeverri; Rita Bottino; Dirk J van der Windt; Jing He; Burcin Ekser; Suyapa Ball; David Ayares; David K C Cooper
Journal:  Xenotransplantation       Date:  2010 Mar-Apr       Impact factor: 3.907

6.  Influence of porcine strain, age, and pH of the isolation medium on porcine pancreatic islet isolation success.

Authors:  A Heiser; K Ulrichs; W Müller-Ruchholtz
Journal:  Transplant Proc       Date:  1994-04       Impact factor: 1.066

7.  Transplantation of porcine fetal pancreas to diabetic patients.

Authors:  C G Groth; O Korsgren; A Tibell; J Tollemar; E Möller; J Bolinder; J Ostman; F P Reinholt; C Hellerström; A Andersson
Journal:  Lancet       Date:  1994-11-19       Impact factor: 79.321

8.  Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates.

Authors:  Bernhard J Hering; Martin Wijkstrom; Melanie L Graham; Maria Hårdstedt; Tor C Aasheim; Tun Jie; Jeffrey D Ansite; Masahiko Nakano; Jane Cheng; Wei Li; Kathleen Moran; Uwe Christians; Colleen Finnegan; Charles D Mills; David E Sutherland; Pratima Bansal-Pakala; Michael P Murtaugh; Nicole Kirchhof; Henk-Jan Schuurman
Journal:  Nat Med       Date:  2006-02-19       Impact factor: 53.440

9.  Parameters for successful pig islet isolation as determined using 68 specific-pathogen-free miniature pigs.

Authors:  Hyoung-Il Kim; Song-Yi Lee; Sang Man Jin; Kang Seok Kim; Jae Eun Yu; Su-Cheong Yeom; Tai Wook Yoon; Jae Hyeon Kim; Jongwon Ha; Chung-Gyu Park; Sang-Joon Kim
Journal:  Xenotransplantation       Date:  2009 Jan-Feb       Impact factor: 3.907

10.  Assessment of some porcine strains as donors of islets of Langerhans.

Authors:  M Sabat; E Godlewska; J Kinasiewicz; A Urbanowicz; T Orłowski
Journal:  Transplant Proc       Date:  2003-09       Impact factor: 1.066
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  6 in total

Review 1.  Pig-to-Primate Islet Xenotransplantation: Past, Present, and Future.

Authors:  Zhengzhao Liu; Wenbao Hu; Tian He; Yifan Dai; Hidetaka Hara; Rita Bottino; David K C Cooper; Zhiming Cai; Lisha Mou
Journal:  Cell Transplant       Date:  2017-02-03       Impact factor: 4.064

Review 2.  Treatment of diabetes with encapsulated pig islets: an update on current developments.

Authors:  Hai-tao Zhu; Lu Lu; Xing-yu Liu; Liang Yu; Yi Lyu; Bo Wang
Journal:  J Zhejiang Univ Sci B       Date:  2015-05       Impact factor: 3.066

3.  Production of genetically modified pigs expressing human insulin and C-peptide as a source of islets for xenotransplantation.

Authors:  Bumrae Cho; Eun-Jin Lee; Sun Mi Ahn; Ghangyong Kim; Sang Hoon Lee; Dal-Young Ji; Jung-Taek Kang
Journal:  Transgenic Res       Date:  2019-08-31       Impact factor: 2.788

Review 4.  Will Genetic Engineering Carry Xenotransplantation of Pig Islets to the Clinic?

Authors:  Elisabeth Kemter; Joachim Denner; Eckhard Wolf
Journal:  Curr Diab Rep       Date:  2018-09-18       Impact factor: 4.810

Review 5.  Nonhuman primate models of type 1 diabetes mellitus for islet transplantation.

Authors:  Haitao Zhu; Liang Yu; Yayi He; Bo Wang
Journal:  J Diabetes Res       Date:  2014-10-20       Impact factor: 4.011

6.  Comparison of Islet Characterization from Use of Standard Crude Collagenase to GMP-Grade Collagenase Enzyme Blends in Preweaned Porcine Islet Isolations.

Authors:  Nicole Corrales; Soomin Park; Hien Lau; Ivana Xu; Colleen Luong; Samuel Rodriguez; Johanna Mönch; Michael Alexander; Jonathan Rt Lakey
Journal:  Cell Transplant       Date:  2020 Jan-Dec       Impact factor: 4.064
  6 in total

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