Literature DB >> 25090572

Architecture and applications of a high resolution gated SPAD image sensor.

Samuel Burri, Yuki Maruyama, Xavier Michalet, Francesco Regazzoni, Claudio Bruschini, Edoardo Charbon.   

Abstract

We present the architecture and three applications of the largest resolution image sensor based on single-photon avalanche diodes (SPADs) published to date. The sensor, fabricated in a high-voltage CMOS process, has a resolution of 512 × 128 pixels and a pitch of 24 μm. The fill-factor of 5% can be increased to 30% with the use of microlenses. For precise control of the exposure and for time-resolved imaging, we use fast global gating signals to define exposure windows as small as 4 ns. The uniformity of the gate edges location is ∼140 ps (FWHM) over the whole array, while in-pixel digital counting enables frame rates as high as 156 kfps. Currently, our camera is used as a highly sensitive sensor with high temporal resolution, for applications ranging from fluorescence lifetime measurements to fluorescence correlation spectroscopy and generation of true random numbers.

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Year:  2014        PMID: 25090572      PMCID: PMC4162351          DOI: 10.1364/OE.22.017573

Source DB:  PubMed          Journal:  Opt Express        ISSN: 1094-4087            Impact factor:   3.894


  8 in total

1.  Phasor imaging with a widefield photon-counting detector.

Authors:  Ryan A Colyer; Oswald H W Siegmund; Anton S Tremsin; John V Vallerga; Shimon Weiss; Xavier Michalet
Journal:  J Biomed Opt       Date:  2012-01       Impact factor: 3.170

2.  Design and characterization of a 256 x 64-pixel single-photon imager in CMOS for a MEMS-based laser scanning time-of-flight sensor.

Authors:  Cristiano Niclass; Kota Ito; Mineki Soga; Hiroyuki Matsubara; Isao Aoyagi; Satoru Kato; Manabu Kagami
Journal:  Opt Express       Date:  2012-05-21       Impact factor: 3.894

Review 3.  Fluorescence lifetime measurements and biological imaging.

Authors:  Mikhail Y Berezin; Samuel Achilefu
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

4.  Microconcentrators to recover fill-factor in image photodetectors with pixel on-board processing circuits.

Authors:  Silvano Donati; Giuseppe Martini; Michele Norgia
Journal:  Opt Express       Date:  2007-12-24       Impact factor: 3.894

5.  Fast single-photon avalanche diode arrays for laser Raman spectroscopy.

Authors:  Jordana Blacksberg; Yuki Maruyama; Edoardo Charbon; George R Rossman
Journal:  Opt Lett       Date:  2011-09-15       Impact factor: 3.776

6.  The performance of 2D array detectors for light sheet based fluorescence correlation spectroscopy.

Authors:  Anand Pratap Singh; Jan Wolfgang Krieger; Jan Buchholz; Edoardo Charbon; Jörg Langowski; Thorsten Wohland
Journal:  Opt Express       Date:  2013-04-08       Impact factor: 3.894

7.  Measurement and modeling of microlenses fabricated on single-photon avalanche diode arrays for fill factor recovery.

Authors:  Juan Mata Pavia; Martin Wolf; Edoardo Charbon
Journal:  Opt Express       Date:  2014-02-24       Impact factor: 3.894

8.  Ultra high-throughput single molecule spectroscopy with a 1024 pixel SPAD.

Authors:  Ryan A Colyer; Giuseppe Scalia; Federica A Villa; Fabrizio Guerrieri; Simone Tisa; Franco Zappa; Sergio Cova; Shimon Weiss; Xavier Michalet
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2011-02-28
  8 in total
  17 in total

1.  Imaging fluorescence (cross-) correlation spectroscopy in live cells and organisms.

Authors:  Jan W Krieger; Anand P Singh; Nirmalya Bag; Christoph S Garbe; Timothy E Saunders; Jörg Langowski; Thorsten Wohland
Journal:  Nat Protoc       Date:  2015-11-05       Impact factor: 13.491

2.  Widefield High Frame Rate Single-Photon SPAD Imagers for SPIM-FCS.

Authors:  Jan Buchholz; Jan Krieger; Claudio Bruschini; Samuel Burri; Andrei Ardelean; Edoardo Charbon; Jörg Langowski
Journal:  Biophys J       Date:  2018-05-10       Impact factor: 4.033

3.  Continuous and discrete phasor analysis of binned or time-gated periodic decays.

Authors:  Xavier Michalet
Journal:  AIP Adv       Date:  2021-03-23       Impact factor: 1.548

4.  Compact solid-state CMOS single-photon detector array for in vivo NIR fluorescence lifetime oncology measurements.

Authors:  H A R Homulle; F Powolny; P L Stegehuis; J Dijkstra; D-U Li; K Homicsko; D Rimoldi; K Muehlethaler; J O Prior; R Sinisi; E Dubikovskaya; E Charbon; C Bruschini
Journal:  Biomed Opt Express       Date:  2016-04-11       Impact factor: 3.732

5.  A 72 × 60 Angle-Sensitive SPAD Imaging Array for Lens-less FLIM.

Authors:  Changhyuk Lee; Ben Johnson; TaeSung Jung; Alyosha Molnar
Journal:  Sensors (Basel)       Date:  2016-09-02       Impact factor: 3.576

6.  Images from Bits: Non-Iterative Image Reconstruction for Quanta Image Sensors.

Authors:  Stanley H Chan; Omar A Elgendy; Xiran Wang
Journal:  Sensors (Basel)       Date:  2016-11-22       Impact factor: 3.576

Review 7.  Compact SPAD-Based Pixel Architectures for Time-Resolved Image Sensors.

Authors:  Matteo Perenzoni; Lucio Pancheri; David Stoppa
Journal:  Sensors (Basel)       Date:  2016-05-23       Impact factor: 3.576

8.  Photon-Counting Arrays for Time-Resolved Imaging.

Authors:  I Michel Antolovic; Samuel Burri; Ron A Hoebe; Yuki Maruyama; Claudio Bruschini; Edoardo Charbon
Journal:  Sensors (Basel)       Date:  2016-06-29       Impact factor: 3.576

9.  A 75-ps Gated CMOS Image Sensor with Low Parasitic Light Sensitivity.

Authors:  Fan Zhang; Hanben Niu
Journal:  Sensors (Basel)       Date:  2016-06-29       Impact factor: 3.576

10.  Single Photon Counting Performance and Noise Analysis of CMOS SPAD-Based Image Sensors.

Authors:  Neale A W Dutton; Istvan Gyongy; Luca Parmesan; Robert K Henderson
Journal:  Sensors (Basel)       Date:  2016-07-20       Impact factor: 3.576

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