H R Hull1,2, J Thornton2, C Paley3, K Navder4, D Gallagher2. 1. Department of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City, KS, USA. 2. New York Obesity Nutrition Research Center, Columbia University, St. Luke's-Roosevelt Hospital, New York, NY, USA. 3. Department of Pediatrics, St. Luke's-Roosevelt Hospital, New York, NY, USA. 4. Department of Nutritional Sciences, Hunter College, New York, NY, USA.
Abstract
BACKGROUND: It is suggested that maternal obesity perpetuates offspring obesity to future generations. OBJECTIVE: To determine whether location of neonate fat mass (FM: central vs. peripheral) is related to total neonate FM and whether maternal obesity influences this relationship. METHODS: Neonate body composition and skin-fold thicknesses were assessed in healthy neonates (n = 371; 1-3 days old). Linear regression models examined the relationship between total FM and location of FM (central vs. peripheral). Location of FM was calculated by skin-folds: peripheral was the sum of (biceps and triceps)/2 and central was represented by the subscapular skin-fold. RESULTS: A significant interaction was found for location of FM and maternal obesity. Holding all predictors constant, in offspring born to non-obese mothers, a 0.5 mm increase in central FM predicted a 15 g greater total FM, whereas a 0.5 mm increase in peripheral FM predicted a 66 g greater total FM. However, in offspring born to obese mothers, a 0.5 mm increase in central FM predicted a 56 g total FM, whereas a 0.5 mm increase in peripheral FM predicted a 14 g greater total FM. CONCLUSIONS: The relationship between total FM and location of FM is influenced by maternal obesity.
BACKGROUND: It is suggested that maternal obesity perpetuates offspring obesity to future generations. OBJECTIVE: To determine whether location of neonate fat mass (FM: central vs. peripheral) is related to total neonate FM and whether maternal obesity influences this relationship. METHODS: Neonate body composition and skin-fold thicknesses were assessed in healthy neonates (n = 371; 1-3 days old). Linear regression models examined the relationship between total FM and location of FM (central vs. peripheral). Location of FM was calculated by skin-folds: peripheral was the sum of (biceps and triceps)/2 and central was represented by the subscapular skin-fold. RESULTS: A significant interaction was found for location of FM and maternal obesity. Holding all predictors constant, in offspring born to non-obese mothers, a 0.5 mm increase in central FM predicted a 15 g greater total FM, whereas a 0.5 mm increase in peripheral FM predicted a 66 g greater total FM. However, in offspring born to obese mothers, a 0.5 mm increase in central FM predicted a 56 g total FM, whereas a 0.5 mm increase in peripheral FM predicted a 14 g greater total FM. CONCLUSIONS: The relationship between total FM and location of FM is influenced by maternal obesity.
Authors: Valerie J Flaherman; Michael W Kuzniewicz; Sherian Li; Eileen Walsh; Charles E McCulloch; Thomas B Newman Journal: Arch Dis Child Fetal Neonatal Ed Date: 2013-07-17 Impact factor: 5.747
Authors: Kendall J Arslanian; Ulai T Fidow; Theresa Atanoa; Take Naseri; Rachel L Duckham; Stephen T McGarvey; Courtney Choy; Nicola L Hawley Journal: Ann Hum Biol Date: 2020-10-18 Impact factor: 1.533