Literature DB >> 25086556

Development of patient-specific molecular imaging phantoms using a 3D printer.

J I Gear1, C Long1, D Rushforth1, S J Chittenden1, C Cummings1, G D Flux1.   

Abstract

PURPOSE: The aim of the study was to investigate rapid prototyping technology for the production of patient-specific, cost-effective liquid fillable phantoms directly from patient CT data.
METHODS: Liver, spleen, and kidney volumes were segmented from patient CT data. Each organ was converted to a shell and filling holes and leg supports were added using computer aided design software and prepared for printing. Additional fixtures were added to the liver to allow lesion inserts to be fixed within the structure. Phantoms were printed from an ultraviolet curable photopolymer using polyjet technology on an Objet EDEN 500V 3D printer.
RESULTS: The final print material is a clear solid acrylic plastic which is watertight, rigid, and sufficiently durable to withstand multiple assembly and scanning protocols. Initial scans of the phantoms have been performed with Tc-99m SPECT and F-18 PET/CT.
CONCLUSIONS: The organ geometry showed good correspondence with anatomical references. The methodology developed can be generally applied to other anatomical or geometrical phantoms for molecular imaging.

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Year:  2014        PMID: 25086556     DOI: 10.1118/1.4887854

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  23 in total

1.  Technical Note: Characterization of custom 3D printed multimodality imaging phantoms.

Authors:  Matthew F Bieniosek; Brian J Lee; Craig S Levin
Journal:  Med Phys       Date:  2015-10       Impact factor: 4.071

2.  Toward a Patient-Specific Traceable Quantification of SPECT/CT-Based Radiopharmaceutical Distributions.

Authors:  Anna-Lena Theisen; Michael Lassmann; Johannes Tran-Gia
Journal:  J Nucl Med       Date:  2021-11-18       Impact factor: 11.082

3.  Application of 3D rapid prototyping technology in posterior corrective surgery for Lenke 1 adolescent idiopathic scoliosis patients.

Authors:  Mingyuan Yang; Chao Li; Yanming Li; Yingchuan Zhao; Xianzhao Wei; Guoyou Zhang; Jianping Fan; Haijian Ni; Ziqiang Chen; Yushu Bai; Ming Li
Journal:  Medicine (Baltimore)       Date:  2015-02       Impact factor: 1.889

4.  Abdo-Man: a 3D-printed anthropomorphic phantom for validating quantitative SIRT.

Authors:  Jonathan I Gear; Craig Cummings; Allison J Craig; Antigoni Divoli; Clive D C Long; Michael Tapner; Glenn D Flux
Journal:  EJNMMI Phys       Date:  2016-08-05

5.  Organ-specific SPECT activity calibration using 3D printed phantoms for molecular radiotherapy dosimetry.

Authors:  Andrew P Robinson; Jill Tipping; David M Cullen; David Hamilton; Richard Brown; Alex Flynn; Christopher Oldfield; Emma Page; Emlyn Price; Andrew Smith; Richard Snee
Journal:  EJNMMI Phys       Date:  2016-07-13

6.  A 3D-printed anatomical pancreas and kidney phantom for optimizing SPECT/CT reconstruction settings in beta cell imaging using 111In-exendin.

Authors:  Wietske Woliner-van der Weg; Laura N Deden; Antoi P W Meeuwis; Maaike Koenrades; Laura H C Peeters; Henny Kuipers; Geert Jan Laanstra; Martin Gotthardt; Cornelis H Slump; Eric P Visser
Journal:  EJNMMI Phys       Date:  2016-12-07

7.  Use of 3D printers to create a patient-specific 3D bolus for external beam therapy.

Authors:  Sarah Burleson; Jamie Baker; An Ting Hsia; Zhigang Xu
Journal:  J Appl Clin Med Phys       Date:  2015-05-08       Impact factor: 2.102

8.  Three-Dimensional Printing for Preoperative Planning and Pedicle Screw Placement in Adult Spinal Deformity: A Systematic Review.

Authors:  Cesar D Lopez; Venkat Boddapati; Nathan J Lee; Marc D Dyrszka; Zeeshan M Sardar; Ronald A Lehman; Lawrence G Lenke
Journal:  Global Spine J       Date:  2020-08-07

9.  A novel phantom technique for evaluating the performance of PET auto-segmentation methods in delineating heterogeneous and irregular lesions.

Authors:  B Berthon; C Marshall; R Holmes; E Spezi
Journal:  EJNMMI Phys       Date:  2015-06-27

10.  Individualized 3D scanning and printing for non-melanoma skin cancer brachytherapy: a financial study for its integration into clinical workflow.

Authors:  Meritxell Arenas; Sebastià Sabater; Andreu Sintas; Monica Arguís; Víctor Hernández; Miguel Árquez; Iolanda López; Àngeles Rovirosa; Doménec Puig
Journal:  J Contemp Brachytherapy       Date:  2017-05-30
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