Literature DB >> 25077117

Trends in use and cost of initial cancer treatment in Ontario: a population-based descriptive study.

Claire de Oliveira1, Karen E Bremner2, Reka Pataky3, Nadia Gunraj4, Mahbubul Haq4, Kelvin Chan5, Winson Y Cheung6, Jeffrey S Hoch7, Stuart Peacock8, Murray D Krahn9.   

Abstract

BACKGROUND: Cancer incidence and treatment-related costs are rising in Canada. We estimated health care use and costs in the first year after diagnosis for patients with 7 common types of cancer in Ontario to examine temporal trends in patterns of care and costs.
METHODS: We selected patients aged 19-44 years who had received a diagnosis of melanoma, breast cancer (female only), testicular cancer or thyroid cancer, in addition to patients aged 45 years and older who had received a diagnosis of breast (female only), prostate, lung or colorectal cancer, between 1997 and 2007. Patients were identified from the Ontario Cancer Registry. Using linked administrative databases, we determined use and costs of chemotherapy, radiotherapy, cancer-related surgery, other admissions to hospital and home care. We adjusted all costs to 2009 Canadian dollars.
RESULTS: We identified 20 821 patients aged 19-44 years and 178 797 patients aged 45 years and older. The greatest increases in costs during the study period were for melanoma, breast cancer, colorectal cancer, lung cancer and prostate cancer (p < 0.05). For prostate and lung cancers, mean costs increased 50% (from $11 490 and $22 037 to $15 170 and $34 473, respectively). Mean costs doubled for breast (from $15 460 and $12 909 to $35 977 and $29 362 for younger and older patients, respectively) and colorectal cancers (from $24 769 to $43 964), and nearly tripled for melanoma (from $3581 to $8934). Costs related to hospital admissions accounted for the largest portion of total costs. The use of chemotherapy, radiotherapy and home care generally increased for all cancers.
INTERPRETATION: The significant increase in mean costs of initial cancer treatment among the patients included in this study was primarily due to more patients receiving adjuvant therapy and home care, and to the increasing expenditures for these services and cancer-related surgeries. Understanding trends in health care use and costs can help policy-makers to take the necessary measures to achieve a more accountable, high-performing health care system.

Entities:  

Year:  2013        PMID: 25077117      PMCID: PMC3986020          DOI: 10.9778/cmajo.20130041

Source DB:  PubMed          Journal:  CMAJ Open        ISSN: 2291-0026


  16 in total

1.  The cost of radiotherapy at an Ontario regional cancer centre: a re-evaluation.

Authors:  C Earle; D Coyle; A Smith; O Agboola; W K Evans
Journal:  Crit Rev Oncol Hematol       Date:  1999-11       Impact factor: 6.312

2.  The 2011 EBCTCG polychemotherapy overview.

Authors:  Carlo Palmieri; Alison Jones
Journal:  Lancet       Date:  2011-12-05       Impact factor: 79.321

3.  Obtaining long-term disease specific costs of care: application to Medicare enrollees diagnosed with colorectal cancer.

Authors:  M L Brown; G F Riley; A L Potosky; R D Etzioni
Journal:  Med Care       Date:  1999-12       Impact factor: 2.983

4.  Realizing the promise of personalized medicine.

Authors:  Mara G Aspinall; Richard G Hamermesh
Journal:  Harv Bus Rev       Date:  2007-10

5.  Using cancer registry data for survival studies: the example of the Ontario Cancer Registry.

Authors:  Stephen Hall; Karleen Schulze; Patti Groome; William Mackillop; Eric Holowaty
Journal:  J Clin Epidemiol       Date:  2005-10-03       Impact factor: 6.437

6.  Costs of treatment for elderly women with early-stage breast cancer in fee-for-service settings.

Authors:  Joan L Warren; Martin L Brown; Michael P Fay; Nicola Schussler; Arnold L Potosky; Gerald F Riley
Journal:  J Clin Oncol       Date:  2002-01-01       Impact factor: 44.544

7.  Evaluation of trends in the cost of initial cancer treatment.

Authors:  Joan L Warren; K Robin Yabroff; Angela Meekins; Marie Topor; Elizabeth B Lamont; Martin L Brown
Journal:  J Natl Cancer Inst       Date:  2008-06-10       Impact factor: 13.506

8.  Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.

Authors:  Bernard Fisher; Stewart Anderson; John Bryant; Richard G Margolese; Melvin Deutsch; Edwin R Fisher; Jong-Hyeon Jeong; Norman Wolmark
Journal:  N Engl J Med       Date:  2002-10-17       Impact factor: 91.245

9.  Trends and predictors of first-line chemotherapy use among elderly patients with advanced non-small cell lung cancer in the United States.

Authors:  Kathleen Lang; Martin D Marciniak; Doug Faries; Michael Stokes; Don Buesching; Craig Earle; Joseph Treat; Nathalie Morissette; David Thompson
Journal:  Lung Cancer       Date:  2008-07-22       Impact factor: 5.705

10.  Understanding the costs of cancer care before and after diagnosis for the 21 most common cancers in Ontario: a population-based descriptive study.

Authors:  Claire de Oliveira; Karen E Bremner; Reka Pataky; Nadia Gunraj; Kelvin Chan; Stuart Peacock; Murray D Krahn
Journal:  CMAJ Open       Date:  2013-01-16
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Authors:  Ashley C Mays; Harrison G Bartels; Paul R Wistermayer; Matt L Rohlfing; Christopher M Gentile; Ralph D'Agostino; Joshua D Waltonen
Journal:  Head Neck       Date:  2017-11-13       Impact factor: 3.147

2.  Cost trajectories for cancer patients.

Authors:  W P Wodchis; E Arthurs; A I Khan; S Gandhi; M MacKinnon; J Sussman
Journal:  Curr Oncol       Date:  2016-02-29       Impact factor: 3.677

3.  Cost-of-illness study for non-small-cell lung cancer using real-world data.

Authors:  S J Seung; M Hurry; S Hassan; R N Walton; W K Evans
Journal:  Curr Oncol       Date:  2019-04-01       Impact factor: 3.677

4.  Cost evaluation of out-of-country care for patients with eating disorders in Ontario: a population-based study.

Authors:  Claire de Oliveira; Erin M Macdonald; Diane Green; Patricia Colton; Marion Olmsted; Susan Bondy; Paul Kurdyak
Journal:  CMAJ Open       Date:  2016-11-03

5.  Cancer drug expenditure in British Columbia and Saskatchewan: a trend analysis.

Authors:  Reka Pataky; David A Tran; Andrea Coronado; Riaz Alvi; Darryl Boehm; Dean A Regier; Stuart Peacock
Journal:  CMAJ Open       Date:  2018-07-27

6.  The economic burden of cancers attributable to tobacco smoking, excess weight, alcohol use, and physical inactivity in Canada.

Authors:  H Krueger; E N Andres; J M Koot; B D Reilly
Journal:  Curr Oncol       Date:  2016-08-12       Impact factor: 3.677

7.  Health system costs for stage-specific breast cancer: a population-based approach.

Authors:  N Mittmann; J M Porter; J Rangrej; S J Seung; N Liu; R Saskin; M C Cheung; N B Leighl; J S Hoch; M Trudeau; W K Evans; K N Dainty; C DeAngelis; C C Earle
Journal:  Curr Oncol       Date:  2014-12       Impact factor: 3.677

8.  EQ-5D Health Utility Scores: Data from a Comprehensive Canadian Cancer Centre.

Authors:  Hiten Naik; Doris Howell; Susie Su; Xin Qiu; M Catherine Brown; Ashlee Vennettilli; Margaret Irwin; Vivien Pat; Hannah Solomon; Tian Wang; Henrique Hon; Lawson Eng; Mary Mahler; Henry Thai; Valerie Ho; Wei Xu; Soo Jin Seung; Nicole Mittmann; Geoffrey Liu
Journal:  Patient       Date:  2017-02       Impact factor: 3.883

9.  Costs of cervical cancer treatment: population-based estimates from Ontario.

Authors:  C Pendrith; A Thind; G S Zaric; S Sarma
Journal:  Curr Oncol       Date:  2016-04-13       Impact factor: 3.677

10.  Costs associated with evaluation of incidental breast lesions identified on computed tomography.

Authors:  Dominik Schramm; Cholpan Jasaabuu; Andreas G Bach; Oliver Tennstedt; Rolf P Spielmann; Alexey Surov
Journal:  Br J Radiol       Date:  2015-12-09       Impact factor: 3.039

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