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Literature DB >> 25073771

Evaluation of two commercially available rapid diagnostic tests for Lyme borreliosis.

P W Smit^1,2, S Kurkela^3,4, M Kuusi⁵, O Vapalahti^3,4,6.

Abstract

The diagnosis of Lyme disease is very complicated and a single diagnostic method cannot exclude infection. We assessed the performance of two commercially available Borrelia burgdorferi rapid diagnostic tests (RDT) in comparison to multiple laboratory-based diagnostic assays using specimens with a gradually increasing probability of Borrelia infection. Based on 200 specimens, the analytical sensitivities for IgG and IgM were 18 and 23% for the Lyme RDT and 24 and 32% for the Borreliose Complete RDT. The sensitivity for detecting diagnosed Lyme borreliosis cases was low (26% Lyme RDT and 32% with the Borreliose Complete RDT respectively), whereas the specificity was good (85% Lyme RDT and 88% Borreliose Complete). Based on this evaluation, the performance of RDTs in detecting Lyme borreliosis appeared to be below that of laboratory-based diagnostics.

Entities: Disease Species

Mesh：

Substances：

Year: 2014 PMID： 25073771 DOI： 10.1007/s10096-014-2217-5

Source DB: PubMed Journal: Eur J Clin Microbiol Infect Dis ISSN： 0934-9723 Impact factor: 3.267

11 in total

Review 1. Diagnostics for the developing world.

Authors: David Mabey; Rosanna W Peeling; Andrew Ustianowski; Mark D Perkins
Journal: Nat Rev Microbiol Date: 2004-03 Impact factor: 60.633

2. A multi-centre evaluation of nine rapid, point-of-care syphilis tests using archived sera.

Authors: A J Herring; R C Ballard; V Pope; R A Adegbola; J Changalucha; D W Fitzgerald; E W Hook; A Kubanova; S Mananwatte; J W Pape; A W Sturm; B West; Y P Yin; R W Peeling
Journal: Sex Transm Infect Date: 2006-11-21 Impact factor: 3.519

3. Evaluation of commercial screening tests and blot assays for the diagnosis of Lyme borreliosis.

Authors: Laurent Busson; Marijke Reynders; Sigi Van den Wijngaert; Hafid Dahma; Marc Decolvenaer; Liesbet Vasseur; Olivier Vandenberg
Journal: Diagn Microbiol Infect Dis Date: 2012-05-04 Impact factor: 2.803

4. Field evaluation of the CRT and ACON chlamydia point-of-care tests in a tropical, low-resource setting.

Authors: D S Hurly; M Buhrer-Skinner; S G Badman; S Bulu; S N Tabrizi; L Tarivonda; R Muller
Journal: Sex Transm Infect Date: 2013-12-13 Impact factor: 3.519

Review 5. Lyme borreliosis.

Authors: Gerold Stanek; Gary P Wormser; Jeremy Gray; Franc Strle
Journal: Lancet Date: 2011-09-06 Impact factor: 79.321

Review 6. Diagnosis of lyme borreliosis.

Authors: Maria E Aguero-Rosenfeld; Guiqing Wang; Ira Schwartz; Gary P Wormser
Journal: Clin Microbiol Rev Date: 2005-07 Impact factor: 26.132

7. EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis.

Authors: A Mygland; U Ljøstad; V Fingerle; T Rupprecht; E Schmutzhard; I Steiner
Journal: Eur J Neurol Date: 2009-11-23 Impact factor: 6.089

8. Large differences between test strategies for the detection of anti-Borrelia antibodies are revealed by comparing eight ELISAs and five immunoblots.

Authors: C W Ang; D W Notermans; M Hommes; A M Simoons-Smit; T Herremans
Journal: Eur J Clin Microbiol Infect Dis Date: 2011-01-27 Impact factor: 3.267

9. Point-of-care tests to strengthen health systems and save newborn lives: the case of syphilis.

Authors: David C Mabey; Kimberly A Sollis; Helen A Kelly; Adele S Benzaken; Edward Bitarakwate; John Changalucha; Xiang-Sheng Chen; Yue-Ping Yin; Patricia J Garcia; Susan Strasser; Namwinga Chintu; Tikki Pang; Fern Terris-Prestholt; Sedona Sweeney; Rosanna W Peeling
Journal: PLoS Med Date: 2012-06-12 Impact factor: 11.069

Evaluation of two commercially available rapid diagnostic tests for Lyme borreliosis.

Review 1. Diagnostics for the developing world.

2. A multi-centre evaluation of nine rapid, point-of-care syphilis tests using archived sera.

3. Evaluation of commercial screening tests and blot assays for the diagnosis of Lyme borreliosis.

4. Field evaluation of the CRT and ACON chlamydia point-of-care tests in a tropical, low-resource setting.

Review 5. Lyme borreliosis.

Review 6. Diagnosis of lyme borreliosis.

7. EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis.

8. Large differences between test strategies for the detection of anti-Borrelia antibodies are revealed by comparing eight ELISAs and five immunoblots.

9. Point-of-care tests to strengthen health systems and save newborn lives: the case of syphilis.

10. Detection of borreliae in archived sera from patients with clinically suspect Lyme disease.

1. Lyme Neuroborreliosis.

2. A concise critical analysis of serologic testing for the diagnosis of lyme disease.

Review 3. Lyme neuroborreliosis-epidemiology, diagnosis and management.

4. Commercial test kits for detection of Lyme borreliosis: a meta-analysis of test accuracy.

5. Guidelines for diagnosis and treatment in neurology - Lyme neuroborreliosis.

6. Application of Bayesian decision-making to laboratory testing for Lyme disease and comparison with testing for HIV.

Review 7. Tick-borne zoonoses and commonly used diagnostic methods in human and veterinary medicine.