Literature DB >> 25069810

IQuant: an automated pipeline for quantitative proteomics based upon isobaric tags.

Bo Wen1, Ruo Zhou, Qiang Feng, Quanhui Wang, Jun Wang, Siqi Liu.   

Abstract

Quantitative proteomics technology based on isobaric tags is playing an important role in proteomic investigation. In this paper, we present an automated software, named IQuant, which integrates a postprocessing tool of protein identification and advanced statistical algorithms to process the MS/MS signals generated from the peptides labeled by isobaric tags and aims at proteomics quantification. The software of IQuant, which is freely downloaded at http://sourceforge.net/projects/iquant/, can run from a graphical user interface and a command-line interface, and can work on both Windows and Linux systems.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords:  Bioinformatics; Isobaric tags; Mass spectrometry; Protein quantification; Technology

Mesh：

Substances：

Year:  2014        PMID： 25069810     DOI： 10.1002/pmic.201300361

Source DB:  PubMed          Journal:  Proteomics        ISSN： 1615-9853            Impact factor:   3.984


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