Literature DB >> 25066780

Characterization of investigators' approach to translational research: a qualitative study.

Doris M Rubio1, Georgeanna F W B Robinson, Victoria A Gilliam, Brian A Primack, Galen E Switzer, Deborah L Seltzer, Wishwa N Kapoor.   

Abstract

BACKGROUND: Little is known about how investigators approach their research programs along the translational research continuum. Many consider the translational continuum to be linear, with research beginning at the bench and concluding with research at the bedside or in the community. We aimed to understand if translational investigators approach and view their research in this fashion.
METHODS: We conducted semistructured individual interviews with 16 graduates of the University of Pittsburgh's Multidisciplinary Clinical Research Scholars Program (KL2) in 2012.
RESULTS: Our research revealed three characteristic models. The first model we called "linear" and represented the traditional approach. The second we called "holistic"; these investigators began with central research questions and sought to explore them in every direction of translation, not necessarily taking linear steps. The third model we called "technical"; in this model, investigators focused on a unique technology or methodology and applied it across multiple research contexts.
CONCLUSION: This study found that there are multiple ways that translational investigators approach their research program. Better understanding of these models can help educators and mentors guide investigators so that they can be more productive in their clinical or translational research career.
© 2014 Wiley Periodicals, Inc.

Entities:  

Keywords:  CTSA; KL2 Scholars Program; bench to bedside; translational continuum; translational research models

Mesh:

Year:  2014        PMID: 25066780      PMCID: PMC4268360          DOI: 10.1111/cts.12196

Source DB:  PubMed          Journal:  Clin Transl Sci        ISSN: 1752-8054            Impact factor:   4.689


  6 in total

Review 1.  Enhancing the quality and credibility of qualitative analysis.

Authors:  M Q Patton
Journal:  Health Serv Res       Date:  1999-12       Impact factor: 3.402

Review 2.  Qualitative research in health care. Assessing quality in qualitative research.

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Journal:  BMJ       Date:  2000-01-01

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Journal:  JAMA       Date:  2000-07-26       Impact factor: 56.272

4.  Evaluating translational research: a process marker model.

Authors:  William Trochim; Cathleen Kane; Mark J Graham; Harold A Pincus
Journal:  Clin Transl Sci       Date:  2011-06       Impact factor: 4.689

5.  Defining translational research: implications for training.

Authors:  Doris McGartland Rubio; Ellie E Schoenbaum; Linda S Lee; David E Schteingart; Paul R Marantz; Karl E Anderson; Lauren Dewey Platt; Adriana Baez; Karin Esposito
Journal:  Acad Med       Date:  2010-03       Impact factor: 6.893

6.  Central challenges facing the national clinical research enterprise.

Authors:  Nancy S Sung; William F Crowley; Myron Genel; Patricia Salber; Lewis Sandy; Louis M Sherwood; Stephen B Johnson; Veronica Catanese; Hugh Tilson; Kenneth Getz; Elaine L Larson; David Scheinberg; E Albert Reece; Harold Slavkin; Adrian Dobs; Jack Grebb; Rick A Martinez; Allan Korn; David Rimoin
Journal:  JAMA       Date:  2003-03-12       Impact factor: 56.272

  6 in total
  1 in total

Review 1.  Mapping the evolving definitions of translational research.

Authors:  Daniel G Fort; Timothy M Herr; Pamela L Shaw; Karen E Gutzman; Justin B Starren
Journal:  J Clin Transl Sci       Date:  2017-02-02
  1 in total

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