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Literature DB >> 2506599

Fixed-interval schedules for drug self-administration in the rat.

Abstract

The practicality of using second-order fixed-interval schedules in studies of heroin reinforcement with rats was examined. Optimum rates of responding were obtained with a dose of 0.03 mg/kg/infusion and an interval duration of 3 min. In addition, schedules consisting of a only a single interval were shown to be practical, leading to response rates comparable to those obtained with cocaine or food as reinforcer.

Entities: Chemical Species

Mesh：

Substances：
Heroin
Cocaine

Year: 1989 PMID： 2506599 DOI： 10.1007/bf00634468

Source DB: PubMed Journal: Psychopharmacology (Berl) ISSN： 0033-3158 Impact factor: 4.530

11 in total

1. Antagonist treatment in nucleus accumbens or periaqueductal grey affects heroin self-administration.

Authors: W A Corrigall; F J Vaccarino
Journal: Pharmacol Biochem Behav Date: 1988-06 Impact factor: 3.533

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Authors: R D Spealman; S R Goldberg
Journal: Annu Rev Pharmacol Toxicol Date: 1978 Impact factor: 13.820

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Authors: N E Goeders; J E Smith
Journal: Science Date: 1983-08-19 Impact factor: 47.728

4. Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats.

Authors: H O Pettit; A Ettenberg; F E Bloom; G F Koob
Journal: Psychopharmacology (Berl) Date: 1984 Impact factor: 4.530

5. Fixed-interval schedules of intravenous cocaine presentation in rats.

Authors: J Dougherty; R Pickens
Journal: J Exp Anal Behav Date: 1973-07 Impact factor: 2.468

6. Heroin self-administration: effects of antagonist treatment in lateral hypothalamus.

Authors: W A Corrigall
Journal: Pharmacol Biochem Behav Date: 1987-08 Impact factor: 3.533

7. Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats.

Authors: D C Roberts; G F Koob
Journal: Pharmacol Biochem Behav Date: 1982-11 Impact factor: 3.533

8. Effects of nicotine on schedule-controlled behaviour. Role of fixed-interval length and modification by mecamylamine and chlorpromazine.

Authors: J M White; C C Ganguzza
Journal: Neuropharmacology Date: 1985-01 Impact factor: 5.250

9. Evidence for opioid mechanisms in the behavioral effects of nicotine.

Authors: W A Corrigall; S Herling; K M Coen
Journal: Psychopharmacology (Berl) Date: 1988 Impact factor: 4.530

10. Heroin self-administration by rats: influence of dose and physical dependence.

Authors: S Dai; W A Corrigall; K M Coen; H Kalant
Journal: Pharmacol Biochem Behav Date: 1989-04 Impact factor: 3.533

7 in total

1. Effects of CB1 and CRF1 receptor antagonists on binge-like eating in rats with limited access to a sweet fat diet: lack of withdrawal-like responses.

Authors: Sarah L Parylak; Pietro Cottone; Valentina Sabino; Kenner C Rice; Eric P Zorrilla
Journal: Physiol Behav Date: 2012-07-06

Review 2. Animal models of drug craving.

Authors: A Markou; F Weiss; L H Gold; S B Caine; G Schulteis; G F Koob
Journal: Psychopharmacology (Berl) Date: 1993 Impact factor: 4.530

6. Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement.

Authors: R B Whitelaw; A Markou; T W Robbins; B J Everitt
Journal: Psychopharmacology (Berl) Date: 1996-10 Impact factor: 4.530

Review 7. Consumption of Substances of Abuse during Pregnancy Increases Consumption in Offspring: Possible Underlying Mechanisms.

Authors: Kinning Poon; Sarah F Leibowitz
Journal: Front Nutr Date: 2016-04-20