Literature DB >> 2506134

Spontaneous mutation results in loss of the cytadhesin (P1) of Mycoplasma pneumoniae.

C J Su1, A Chavoya, J B Baseman.   

Abstract

The cytadhesin (P1) structural gene of a spontaneous mutant of Mycoplasma pneumoniae which displayed a P1-negative phenotype was analyzed. An extra adenine was discovered in a stretch of normally seven adenines near the N-terminal region of the mutant P1 structural gene. The frameshift mutation resulted in the early termination of protein translation. Possible causes of the mutation are discussed.

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Year:  1989        PMID： 2506134      PMCID： PMC260797          DOI： 10.1128/iai.57.10.3237-3239.1989

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  21 in total

1.  Growth on artificial medium of an agent associated with atypical pneumonia and its identification as a PPLO.

Authors:  R M CHANOCK; L HAYFLICK; M F BARILE
Journal:  Proc Natl Acad Sci U S A       Date:  1962-01-15       Impact factor: 11.205

2.  Inhibition of mycoplasma pneumoniae hemadsorption and adherence to respiratory epithelium by antibodies to a membrane protein.

Authors:  D C Krause; J B Baseman
Journal:  Infect Immun       Date:  1983-03       Impact factor: 3.441

3.  Mycoplasma pneumoniae infection: role of a surface protein in the attachment organelle.

Authors:  P C Hu; R M Cole; Y S Huang; J A Graham; D E Gardner; A M Collier; W A Clyde
Journal:  Science       Date:  1982-04-16       Impact factor: 47.728

4.  Identification of Mycoplasma pneumoniae proteins associated with hemadsorption and virulence.

Authors:  D C Krause; D K Leith; R M Wilson; J B Baseman
Journal:  Infect Immun       Date:  1982-03       Impact factor: 3.441

5.  Mycoplasma pneumoniae adhesin localized to tip structure by monoclonal antibody.

Authors:  J Feldner; U Göbel; W Bredt
Journal:  Nature       Date:  1982-08-19       Impact factor: 49.962

6.  A system for shotgun DNA sequencing.

Authors:  J Messing; R Crea; P H Seeburg
Journal:  Nucleic Acids Res       Date:  1981-01-24       Impact factor: 16.971

7.  Phylogenetic analysis of the mycoplasmas.

Authors:  C R Woese; J Maniloff; L B Zablen
Journal:  Proc Natl Acad Sci U S A       Date:  1980-01       Impact factor: 11.205

8.  Mechanisms of spontaneous and induced frameshift mutation in bacteriophage T4.

Authors:  G Streisinger; J Owen
Journal:  Genetics       Date:  1985-04       Impact factor: 4.562

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  Molecular basis for cytadsorption of Mycoplasma pneumoniae.

Authors:  J B Baseman; R M Cole; D C Krause; D K Leith
Journal:  J Bacteriol       Date:  1982-09       Impact factor: 3.490
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  13 in total

1.  Mycoplasma pneumoniae P1 type 1- and type 2-specific sequences within the P1 cytadhesin gene of individual strains.

Authors:  J W Dorigo-Zetsma; B Wilbrink; J Dankert; S A Zaat
Journal:  Infect Immun       Date:  2001-09       Impact factor: 3.441

2.  Genome size of Mycoplasma genitalium.

Authors:  C J Su; J B Baseman
Journal:  J Bacteriol       Date:  1990-08       Impact factor: 3.490

3.  Identification and complementation of a mutation associated with loss of Mycoplasma pneumoniae virulence-specific proteins B and C.

Authors:  Robert H Waldo; Jarrat L Jordan; Duncan C Krause
Journal:  J Bacteriol       Date:  2005-01       Impact factor: 3.490

4.  Synthesis, stability, and function of cytadhesin P1 and accessory protein B/C complex of Mycoplasma pneumoniae.

Authors:  Robert H Waldo; Duncan C Krause
Journal:  J Bacteriol       Date:  2006-01       Impact factor: 3.490

5.  Protein P200 is dispensable for Mycoplasma pneumoniae hemadsorption but not gliding motility or colonization of differentiated bronchial epithelium.

Authors:  Jarrat L Jordan; How-Yi Chang; Mitchell F Balish; Lynley S Holt; Stephanie R Bose; Benjamin M Hasselbring; Robert H Waldo; Thomas M Krunkosky; Duncan C Krause
Journal:  Infect Immun       Date:  2006-10-16       Impact factor: 3.441

6.  Biofunctional domains of the Mycoplasma pneumoniae P30 adhesin.

Authors:  S F Dallo; A L Lazzell; A Chavoya; S P Reddy; J B Baseman
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

7.  Mycoplasma genitalium P140 and P110 cytadhesins are reciprocally stabilized and required for cell adhesion and terminal-organelle development.

Authors:  Raul Burgos; Oscar Q Pich; Mario Ferrer-Navarro; Joel B Baseman; Enrique Querol; Jaume Piñol
Journal:  J Bacteriol       Date:  2006-10-06       Impact factor: 3.490

8.  A spontaneous hemadsorption-negative mutant of Mycoplasma pneumoniae exhibits a truncated adhesin-related 30-kilodalton protein and lacks the cytadherence-accessory protein HMW1.

Authors:  G Layh-Schmitt; H Hilbert; E Pirkl
Journal:  J Bacteriol       Date:  1995-02       Impact factor: 3.490

Review 9.  Molecular biology and pathogenicity of mycoplasmas.

Authors:  S Razin; D Yogev; Y Naot
Journal:  Microbiol Mol Biol Rev       Date:  1998-12       Impact factor: 11.056

10.  Possible origin of sequence divergence in the P1 cytadhesin gene of Mycoplasma pneumoniae.

Authors:  C J Su; S F Dallo; A Chavoya; J B Baseman
Journal:  Infect Immun       Date:  1993-03       Impact factor: 3.441
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