| Literature DB >> 25056363 |
James W Keck1, Lisa R Bulkow2, Gregory A Raczniak3, Susan E Negus4, Carolyn L Zanis2, Michael G Bruce2, Philip R Spradling5, Eyasu H Teshale5, Brian J McMahon6.
Abstract
Hepatitis B antibody persistence was assessed in individuals who had previously received a vaccine booster. We measured hepatitis B surface antigen antibody (anti-HBs) levels 7 to 9 years post-hepatitis B booster in individuals with primary vaccination at birth. While 95 (91.3%) of 104 participants had detectable anti-HBs (minimum, 0.1 mIU/ml; maximum, 1,029 mIU/ml), only 43 (41%) had protective levels of ≥10 mIU/ml. Pre- and week 4 postbooster anti-HBs levels were significant predictors of hepatitis B immunity at follow-up (P < 0.001). Almost all participants had detectable anti-HBs 7 to 9 years after the hepatitis B vaccine booster, but less than half had levels ≥10 mIU/ml.Entities:
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Year: 2014 PMID: 25056363 PMCID: PMC4178570 DOI: 10.1128/CVI.00263-14
Source DB: PubMed Journal: Clin Vaccine Immunol ISSN: 1556-679X