| Literature DB >> 25055381 |
Ninon Burgos, M Jorge Cardoso, Kris Thielemans, Marc Modat, Stefano Pedemonte, John Dickson, Anna Barnes, Rebekah Ahmed, Colin J Mahoney, Jonathan M Schott, John S Duncan, David Atkinson, Simon R Arridge, Brian F Hutton, Sebastien Ourselin.
Abstract
Attenuation correction is an essential requirement for quantification of positron emission tomography (PET) data. In PET/CT acquisition systems, attenuation maps are derived from computed tomography (CT) images. However, in hybrid PET/MR scanners, magnetic resonance imaging (MRI) images do not directly provide a patient-specific attenuation map. The aim of the proposed work is to improve attenuation correction for PET/MR scanners by generating synthetic CTs and attenuation maps. The synthetic images are generated through a multi-atlas information propagation scheme, locally matching the MRI-derived patient's morphology to a database of MRI/CT pairs, using a local image similarity measure. Results show significant improvements in CT synthesis and PET reconstruction accuracy when compared to a segmentation method using an ultrashort-echo-time MRI sequence and to a simplified atlas-based method.Entities:
Mesh：
Year: 2014 PMID： 25055381 DOI： 10.1109/TMI.2014.2340135
Source DB: PubMed Journal: IEEE Trans Med Imaging ISSN： 0278-0062 Impact factor: 10.048