Literature DB >> 25052778

Microarray immobilization of biomolecules using a fast trans-cyclooctene (TCO)-tetrazine reaction.

Ping Wang1, Zhenkun Na, Jiaqi Fu, Chelsea Y J Tan, Huatang Zhang, Shao Q Yao, Hongyan Sun.   

Abstract

By anchoring 1,2,4,5-tetrazine-containing biomolecules onto trans-cyclooctene (TCO)-functionalized slides, a site-specific microarray immobilization approach is described in this study. Compared with existing immobilization methods, our approach offers several distinctive features, including fast kinetics and high chemoselectivity.

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Year:  2014        PMID： 25052778     DOI： 10.1039/c4cc03838j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Faster Surface Ligation Reactions Improve Immobilized Enzyme Structure and Activity.

Authors:  Andres F Chaparro Sosa; Riley M Bednar; Ryan A Mehl; Daniel K Schwartz; Joel L Kaar
Journal:  J Am Chem Soc       Date:  2021-04-29       Impact factor: 15.419

2.  Approach Matters: The Kinetics of Interfacial Inverse-Electron Demand Diels-Alder Reactions.

Authors:  Rickdeb Sen; Digvijay Gahtory; Jorge Escorihuela; Judith Firet; Sidharam P Pujari; Han Zuilhof
Journal:  Chemistry       Date:  2017-08-23       Impact factor: 5.236

Review 3.  Thiol-ene and photo-cleavage chemistry for controlled presentation of biomolecules in hydrogels.

Authors:  Joseph C Grim; Ian A Marozas; Kristi S Anseth
Journal:  J Control Release       Date:  2015-08-24       Impact factor: 9.776

4.  Extracellular vesicles on demand (EVOD) chip for screening and quantification of cancer-associated extracellular vesicles.

Authors:  Yoon-Tae Kang; Thomas Hadlock; Shruti Jolly; Sunitha Nagrath
Journal:  Biosens Bioelectron       Date:  2020-08-23       Impact factor: 12.545
  4 in total

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