Literature DB >> 25051903

Gender-differences in disease distribution and outcome in hospitalized elderly: data from the REPOSI study.

S Corrao1, P Santalucia2, C Argano3, C D Djade4, E Barone3, M Tettamanti5, L Pasina5, C Franchi5, T Kamal Eldin5, A Marengoni6, F Salerno7, M Marcucci8, P M Mannucci9, A Nobili5.   

Abstract

BACKGROUND AND
PURPOSE: Women live longer and outnumber men. On the other hand, older women develop more chronic diseases and conditions such as arthritis, osteoporosis and depression, leading to a greater number of years of living with disabilities. The aim of this study was to describe whether or not there are gender differences in the demographic profile, disease distribution and outcome in a population of hospitalized elderly people.
METHODS: Retrospective observational study including all patients recruited for the REPOSI study in the year 2010. Analyses are referred to the whole group and gender categorization was applied.
RESULTS: A total of 1380 hospitalized elderly subjects, 50.5% women and 49.5% men, were considered. Women were older than men, more often widow and living alone or in nursing homes. Disease distribution showed that malignancy, diabetes, coronary artery disease, chronic kidney disease and chronic obstructive pulmonary disease were more frequent in men, but hypertension, osteoarthritis, anemia and depression were more frequent in women. Severity and comorbidity indexes according to the Cumulative Illness Rating Scale (CIRS-s and CIRS-c) were higher in men, while cognitive impairment evaluated by the Short Blessed Test (SBT), mood disorders by the Geriatric Depression Scale (GDS) and disability in daily life measured by Barthel Index (BI) were worse in women. In-hospital and 3-month mortality rates were higher in men.
CONCLUSIONS: Our study showed a gender dimorphism in the demographic and morbidity profiles of hospitalized elderly people, emphasizing once more the need for a personalized process of healthcare.
Copyright © 2014 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Disease distribution; Elderly; In-hospital mortality; Sex-gender difference

Mesh:

Year:  2014        PMID: 25051903     DOI: 10.1016/j.ejim.2014.06.027

Source DB:  PubMed          Journal:  Eur J Intern Med        ISSN: 0953-6205            Impact factor:   4.487


  35 in total

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Review 2.  Polypharmacy in older people: lessons from 10 years of experience with the REPOSI register.

Authors:  Pier Mannuccio Mannucci; Alessandro Nobili; Luca Pasina
Journal:  Intern Emerg Med       Date:  2018-08-31       Impact factor: 3.397

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