Literature DB >> 25047799

Highly selective fluorescence off-on probes for biothiols and imaging in live cells.

Di Zhang1, Wei Chen, Jianming Kang, Yong Ye, Yufen Zhao, Ming Xian.   

Abstract

Three sulfonyl benzothiazole-based fluorescent probes (, , and ) for the detection of biothiols (cysteine, homocysteine, and glutathione) are developed based on thiol-mediated nucleophilic aromatic substitutions. The probes exhibited good selectivity and sensitivity toward biothiols over other analytes. The probes were successfully applied for visualizing endogenous thiols in living cells.

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Year:  2014        PMID： 25047799      PMCID： PMC4134666          DOI： 10.1039/c4ob01031k

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  33 in total

1.  Conjugate addition/cyclization sequence enables selective and simultaneous fluorescence detection of cysteine and homocysteine.

Authors:  Xiaofeng Yang; Yixing Guo; Robert M Strongin
Journal:  Angew Chem Int Ed Engl       Date:  2011-09-20       Impact factor: 15.336

2.  Oxidized redox state of glutathione in the endoplasmic reticulum.

Authors:  C Hwang; A J Sinskey; H F Lodish
Journal:  Science       Date:  1992-09-11       Impact factor: 47.728

Review 3.  Fluorescent and colorimetric probes for detection of thiols.

Authors:  Xiaoqiang Chen; Ying Zhou; Xiaojun Peng; Juyoung Yoon
Journal:  Chem Soc Rev       Date:  2010-03-03       Impact factor: 54.564

4.  Analytical determination of homocysteine: a review.

Authors:  Olga Nekrassova; Nathan S Lawrence; Richard G Compton
Journal:  Talanta       Date:  2003-08-29       Impact factor: 6.057

5.  A reductive ligation based fluorescent probe for S-nitrosothiols.

Authors:  Di Zhang; Wei Chen; Zhengrui Miao; Yong Ye; Yufen Zhao; S Bruce King; Ming Xian
Journal:  Chem Commun (Camb)       Date:  2014-05-14       Impact factor: 6.222

Review 6.  Chromogenic and fluorogenic chemosensors and reagents for anions. A comprehensive review of the years 2010-2011.

Authors:  Luis E Santos-Figueroa; María E Moragues; Estela Climent; Alessandro Agostini; Ramón Martínez-Máñez; Félix Sancenón
Journal:  Chem Soc Rev       Date:  2013-02-11       Impact factor: 54.564

7.  Glutathione deficiency is associated with impaired survival in HIV disease.

Authors:  L A Herzenberg; S C De Rosa; J G Dubs; M Roederer; M T Anderson; S W Ela; S C Deresinski; L A Herzenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

8.  Ring opening of pymisyl-protected aziridines with organocuprates.

Authors:  Jan Bornholdt; Jakob Felding; Rasmus P Clausen; Jesper L Kristensen
Journal:  Chemistry       Date:  2010-11-02       Impact factor: 5.236

9.  Determination of non-protein cysteine in human serum by a designed BODIPY-based fluorescent probe.

Authors:  Jinxin Lu; Chengdong Sun; Wei Chen; Huimin Ma; Wen Shi; Xiaohua Li
Journal:  Talanta       Date:  2010-11-18       Impact factor: 6.057

10.  A dual emission fluorescent probe enables simultaneous detection of glutathione and cysteine/homocysteine.

Authors:  Xiao-Feng Yang; Qian Huang; Yaogang Zhong; Zheng Li; Hua Li; Mark Lowry; Jorge O Escobedo; Robert M Strongin
Journal:  Chem Sci       Date:  2014-06-01       Impact factor: 9.825
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  2 in total

1.  Novel Boronate Probe Based on 3-Benzothiazol-2-yl-7-hydroxy-chromen-2-one for the Detection of Peroxynitrite and Hypochlorite.

Authors:  Julia Modrzejewska; Marcin Szala; Aleksandra Grzelakowska; Małgorzata Zakłos-Szyda; Jacek Zielonka; Radosław Podsiadły
Journal:  Molecules       Date:  2021-09-30       Impact factor: 4.411

2.  A modular template for the design of thiol-triggered sensors and prodrugs.

Authors:  Jessica Renee Knight; Yingying Wang; Shi Xu; Wei Chen; Clifford E Berkman; Ming Xian
Journal:  Spectrochim Acta A Mol Biomol Spectrosc       Date:  2020-10-13       Impact factor: 4.098
  2 in total

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