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Literature DB >> 2504779

Sensitivity and specificity of pooled versus individual sera in a human immunodeficiency virus antibody prevalence study.

B Cahoon-Young¹, A Chandler, T Livermore, J Gaudino, R Benjamin.

Abstract

We evaluated the efficacy of testing pooled versus individual sera for the detection of human immunodeficiency virus antibody. A total of 5,000 individual specimens and 500 pools of 10 specimens each were assayed by an enzyme-linked immunosorbent assay. There was complete agreement in human immunodeficiency virus enzyme-linked immunosorbent assay reactivity for pooled versus individual specimens. An estimated savings of 60 to 80% (labor and supplies) can be realized dependent upon pooling and assay format.

Entities: Disease Species

Mesh：

Substances：
HIV Antibodies

Year: 1989 PMID： 2504779 PMCID： PMC267694 DOI： 10.1128/jcm.27.8.1893-1895.1989

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

13 in total

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Journal: Lancet Date: 1986-05-17 Impact factor: 79.321

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3. Use of seroconversion panels to estimate delay in detection of anti-human immunodeficiency virus antibodies by enzyme-linked immunosorbent assay of pooled compared to singleton serum samples.

Authors: Lena Novack; Noya Galai; Arieh Yaari; Mordechai Orgel; Eilat Shinar; Batia Sarov
Journal: J Clin Microbiol Date: 2006-08 Impact factor: 5.948

4. Prevalence estimation subject to misclassification: the mis-substitution bias and some remedies.

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5. Pooled nucleic acid testing to identify antiretroviral treatment failure during HIV infection.

Authors: Susanne May; Anthony Gamst; Richard Haubrich; Constance Benson; Davey M Smith
Journal: J Acquir Immune Defic Syndr Date: 2010-02 Impact factor: 3.731

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Journal: Eur J Clin Microbiol Infect Dis Date: 1994-03 Impact factor: 3.267

10. COVID-19 prevalence estimation by random sampling in population - optimal sample pooling under varying assumptions about true prevalence.

Authors: Ola Brynildsrud
Journal: BMC Med Res Methodol Date: 2020-07-23 Impact factor: 4.615