Literature DB >> 25043038

HIV: Early treatment may not be early enough.

Kai Deng1, Robert F Siliciano2.   

Abstract

Mesh:

Year:  2014        PMID: 25043038     DOI: 10.1038/nature13647

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


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  15 in total

1.  Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy.

Authors:  D Finzi; J Blankson; J D Siliciano; J B Margolick; K Chadwick; T Pierson; K Smith; J Lisziewicz; F Lori; C Flexner; T C Quinn; R E Chaisson; E Rosenberg; B Walker; S Gange; J Gallant; R F Siliciano
Journal:  Nat Med       Date:  1999-05       Impact factor: 53.440

2.  Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

Authors:  Janet D Siliciano; Joleen Kajdas; Diana Finzi; Thomas C Quinn; Karen Chadwick; Joseph B Margolick; Colin Kovacs; Stephen J Gange; Robert F Siliciano
Journal:  Nat Med       Date:  2003-05-18       Impact factor: 53.440

Review 3.  The challenge of finding a cure for HIV infection.

Authors:  Douglas D Richman; David M Margolis; Martin Delaney; Warner C Greene; Daria Hazuda; Roger J Pomerantz
Journal:  Science       Date:  2009-03-06       Impact factor: 47.728

4.  Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy.

Authors:  T W Chun; L Stuyver; S B Mizell; L A Ehler; J A Mican; M Baseler; A L Lloyd; M A Nowak; A S Fauci
Journal:  Proc Natl Acad Sci U S A       Date:  1997-11-25       Impact factor: 11.205

5.  Absence of detectable HIV-1 viremia after treatment cessation in an infant.

Authors:  Deborah Persaud; Hannah Gay; Carrie Ziemniak; Ya Hui Chen; Michael Piatak; Tae-Wook Chun; Matthew Strain; Douglas Richman; Katherine Luzuriaga
Journal:  N Engl J Med       Date:  2013-10-23       Impact factor: 91.245

6.  Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts.

Authors:  Laurent Hocqueloux; Véronique Avettand-Fènoël; Sophie Jacquot; Thierry Prazuck; Eric Legac; Adeline Mélard; Mohamadou Niang; Catherine Mille; Gwenaël Le Moal; Jean-Paul Viard; Christine Rouzioux
Journal:  J Antimicrob Chemother       Date:  2013-01-20       Impact factor: 5.790

7.  Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection.

Authors:  T W Chun; D Engel; M M Berrey; T Shea; L Corey; A S Fauci
Journal:  Proc Natl Acad Sci U S A       Date:  1998-07-21       Impact factor: 11.205

8.  Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection.

Authors:  Jintanat Ananworanich; Alexandra Schuetz; Claire Vandergeeten; Irini Sereti; Mark de Souza; Rungsun Rerknimitr; Robin Dewar; Mary Marovich; Frits van Griensven; Rafick Sekaly; Suteeraporn Pinyakorn; Nittaya Phanuphak; Rapee Trichavaroj; Wiriya Rutvisuttinunt; Nitiya Chomchey; Robert Paris; Sheila Peel; Victor Valcour; Frank Maldarelli; Nicolas Chomont; Nelson Michael; Praphan Phanuphak; Jerome H Kim
Journal:  PLoS One       Date:  2012-03-30       Impact factor: 3.240

9.  Immune clearance of highly pathogenic SIV infection.

Authors:  Scott G Hansen; Michael Piatak; Abigail B Ventura; Colette M Hughes; Roxanne M Gilbride; Julia C Ford; Kelli Oswald; Rebecca Shoemaker; Yuan Li; Matthew S Lewis; Awbrey N Gilliam; Guangwu Xu; Nathan Whizin; Benjamin J Burwitz; Shannon L Planer; John M Turner; Alfred W Legasse; Michael K Axthelm; Jay A Nelson; Klaus Früh; Jonah B Sacha; Jacob D Estes; Brandon F Keele; Paul T Edlefsen; Jeffrey D Lifson; Louis J Picker
Journal:  Nature       Date:  2013-09-11       Impact factor: 49.962

10.  Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys.

Authors:  James B Whitney; Alison L Hill; Srisowmya Sanisetty; Pablo Penaloza-MacMaster; Jinyan Liu; Mayuri Shetty; Lily Parenteau; Crystal Cabral; Jennifer Shields; Stephen Blackmore; Jeffrey Y Smith; Amanda L Brinkman; Lauren E Peter; Sheeba I Mathew; Kaitlin M Smith; Erica N Borducchi; Daniel I S Rosenbloom; Mark G Lewis; Jillian Hattersley; Bei Li; Joseph Hesselgesser; Romas Geleziunas; Merlin L Robb; Jerome H Kim; Nelson L Michael; Dan H Barouch
Journal:  Nature       Date:  2014-07-20       Impact factor: 49.962

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  11 in total

1.  The HEPT Analogue WPR-6 Is Active against a Broad Spectrum of Nonnucleoside Reverse Transcriptase Drug-Resistant HIV-1 Strains of Different Serotypes.

Authors:  Weisi Xu; Jianxiong Zhao; Jianping Sun; Qianqian Yin; Yan Wang; Yang Jiao; Junyi Liu; Shibo Jiang; Yiming Shao; Xiaowei Wang; Liying Ma
Journal:  Antimicrob Agents Chemother       Date:  2015-06-08       Impact factor: 5.191

Review 2.  Broad Spectrum Mixed Lineage Kinase Type 3 Inhibition and HIV-1 Persistence in Macrophages.

Authors:  Priyanka Saminathan; Bhavesh D Kevadiya; Daniel F Marker; Howard E Gendelman; Santhi Gorantla; Harris A Gelbard
Journal:  J Neuroimmune Pharmacol       Date:  2019-01-07       Impact factor: 4.147

Review 3.  How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs?

Authors:  Jintanat Ananworanich; Karine Dubé; Nicolas Chomont
Journal:  Curr Opin HIV AIDS       Date:  2015-01       Impact factor: 4.283

Review 4.  Dynamic models of viral replication and latency.

Authors:  Pejman Mohammadi; Angela Ciuffi; Niko Beerenwinkel
Journal:  Curr Opin HIV AIDS       Date:  2015-03       Impact factor: 4.283

Review 5.  Eradication of HIV-1 from the macrophage reservoir: an uncertain goal?

Authors:  Wasim Abbas; Muhammad Tariq; Mazhar Iqbal; Amit Kumar; Georges Herbein
Journal:  Viruses       Date:  2015-03-31       Impact factor: 5.048

6.  Counteracting Akt Activation by HIV Protease Inhibitors in Monocytes/Macrophages.

Authors:  Sébastien Pasquereau; Amit Kumar; Wasim Abbas; Georges Herbein
Journal:  Viruses       Date:  2018-04-13       Impact factor: 5.048

7.  Provirus reactivation is impaired in HIV-1 infected individuals on treatment with dasatinib and antiretroviral therapy.

Authors:  Lorena Vigón; Paula Martínez-Román; Sara Rodríguez-Mora; Montserrat Torres; María C Puertas; Elena Mateos; María Salgado; Antonio Navarro; Matilde Sánchez-Conde; Juan Ambrosioni; Miguel Cervero; Christoph Wyen; Christian Hoffmann; José M Miró; José Alcamí; Daniel Podzamczer; Valentín García-Gutiérrez; Javier Martínez-Picado; Verónica Briz; María Rosa López-Huertas; Vicente Planelles; Mayte Coiras
Journal:  Biochem Pharmacol       Date:  2021-06-26       Impact factor: 6.100

8.  Hiding in plain sight - platelets, the silent carriers of HIV-1.

Authors:  Yvonne Baumer; Tina M Weatherby; Brooks I Mitchell; Ivo N SahBandar; Thomas A Premeaux; D'Antoni Michelle L; Cristhian A Gutierrez-Huerta; Tiffany M Powell-Wiley; Timothy R Brown; William A Boisvert; Cecilia M Shikuma; Lishomwa C Ndhlovu
Journal:  Platelets       Date:  2020-11-23       Impact factor: 4.236

9.  Cellular defense against latent colonization foiled by human cytomegalovirus UL138 protein.

Authors:  Song Hee Lee; Emily R Albright; Jeong-Hee Lee; Derek Jacobs; Robert F Kalejta
Journal:  Sci Adv       Date:  2015-11-27       Impact factor: 14.136

10.  Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.

Authors:  Amit Kumar; Wasim Abbas; Laurence Colin; Kashif Aziz Khan; Sophie Bouchat; Audrey Varin; Anis Larbi; Jean-Stéphane Gatot; Kabamba Kabeya; Caroline Vanhulle; Nadège Delacourt; Sébastien Pasquereau; Laurie Coquard; Alexandra Borch; Renate König; Nathan Clumeck; Stephane De Wit; Olivier Rohr; Christine Rouzioux; Tamas Fulop; Carine Van Lint; Georges Herbein
Journal:  Sci Rep       Date:  2016-04-14       Impact factor: 4.379

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