A Langenbruch1, M A Radtke, M Krensel, A Jacobi, K Reich, M Augustin. 1. IVDP - Institute for Health Services Research in Dermatology and Nursing, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246, Hamburg, Germany.
Abstract
BACKGROUND: Patients with psoriatic arthritis (PsA) suffer from increased burden of disease and impairments in quality of life. Early detection and treatment of PsA could contribute to the prevention of clinical and radiological progression. OBJECTIVES: To analyse the predictive value of clinical and patient-reported outcomes for concomitant PsA in a population-based cohort of patients with psoriasis. METHODS: We performed a retrospective analysis of data from three independent national cross-sectional studies on health care in psoriasis and PsA, conducted in Germany in the years 2005, 2007 and 2008. Patients with psoriasis were included in the study by dermatologists (n = 3520) and via the German patient advocacy group for psoriasis (n = 2449). In all studies, psoriasis history, clinical findings, PsA, nail involvement, health care and patient-reported outcomes were collected with standardized questionnaires. RESULTS: In the regression model on 4146 patients the strongest predictors for concomitant PsA were nail involvement [odds ratio (OR) 2·93, 95% confidence interval (CI) 2·51-3·42, P < 0·001] and inpatient hospital treatment (OR 1·63, 95% CI 1·38-1·93, P < 0·001). By contrast, scalp involvement was not a significant predictor. CONCLUSIONS: Patients with psoriasis seen by dermatologists and those in patient advocacy groups show clinical indicators of PsA, the most predictive being nail disease. In practice, a comprehensive assessment of clinical findings associated with PsA is needed.
BACKGROUND:Patients with psoriatic arthritis (PsA) suffer from increased burden of disease and impairments in quality of life. Early detection and treatment of PsA could contribute to the prevention of clinical and radiological progression. OBJECTIVES: To analyse the predictive value of clinical and patient-reported outcomes for concomitant PsA in a population-based cohort of patients with psoriasis. METHODS: We performed a retrospective analysis of data from three independent national cross-sectional studies on health care in psoriasis and PsA, conducted in Germany in the years 2005, 2007 and 2008. Patients with psoriasis were included in the study by dermatologists (n = 3520) and via the German patient advocacy group for psoriasis (n = 2449). In all studies, psoriasis history, clinical findings, PsA, nail involvement, health care and patient-reported outcomes were collected with standardized questionnaires. RESULTS: In the regression model on 4146 patients the strongest predictors for concomitant PsA were nail involvement [odds ratio (OR) 2·93, 95% confidence interval (CI) 2·51-3·42, P < 0·001] and inpatient hospital treatment (OR 1·63, 95% CI 1·38-1·93, P < 0·001). By contrast, scalp involvement was not a significant predictor. CONCLUSIONS:Patients with psoriasis seen by dermatologists and those in patient advocacy groups show clinical indicators of PsA, the most predictive being nail disease. In practice, a comprehensive assessment of clinical findings associated with PsA is needed.
Authors: Piero Ruscitti; Maria Esposito; Camilla Gianneramo; Paola Cipriani; Antonio Barile; Maria Concetta Fargnoli; Ilenia Di Cola; Andrea De Berardinis; Andrea Martinese; Gerard Nkamtse Tochap; Alessandro Conforti; Carlo Masciocchi Journal: Radiol Med Date: 2022-10-19 Impact factor: 6.313
Authors: Yong Beom Choe; Chul Jong Park; Dae Young Yu; Youngdoe Kim; Hyun Jeong Ju; Sang Woong Youn; Joo-Heung Lee; Byung Soo Kim; Seong Jun Seo; Seok-Kweon Yun; Joonsoo Park; Nack In Kim; Jai Il Youn; Seok-Jong Lee; Min-Geol Lee; Kwang Joong Kim; Young Suck Ro; Hae Jun Song; Bong Seok Shin; Sung Ku Ahn; Ji Yeoun Lee; Young Ho Won; Min Soo Jang; Ki Ho Kim; Myung Hwa Kim; Tae Yoon Kim; Jee-Ho Choi Journal: Ann Dermatol Date: 2019-01-02 Impact factor: 1.444