Literature DB >> 25037051

(Post-)genomics approaches in fungal research.

María Victoria Aguilar-Pontes, Ronald P de Vries, Miaomiao Zhou.   

Abstract

To date, hundreds of fungal genomes have been sequenced and many more are in progress. This wealth of genomic information has provided new directions to study fungal biodiversity. However, to further dissect and understand the complicated biological mechanisms involved in fungal life styles, functional studies beyond genomes are required. Thanks to the developments of current -omics techniques, it is possible to produce large amounts of fungal functional data in a high-throughput fashion (e.g. transcriptome, proteome, etc.). The increasing ease of creating -omics data has also created a major challenge for downstream data handling and analysis. Numerous databases, tools and software have been created to meet this challenge. Facing such a richness of techniques and information, hereby we provide a brief roadmap on current wet-lab and bioinformatics approaches to study functional genomics in fungi.
© The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Keywords:  -omics data analysis; fungal bioinformatics; fungal genomes; next-generation sequencing; post-genomic analysis

Mesh:

Year:  2014        PMID: 25037051     DOI: 10.1093/bfgp/elu028

Source DB:  PubMed          Journal:  Brief Funct Genomics        ISSN: 2041-2649            Impact factor:   4.241


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