| Literature DB >> 25035497 |
Frédéric Choulet1, Adriana Alberti2, Sébastien Theil3, Natasha Glover3, Valérie Barbe2, Josquin Daron3, Lise Pingault3, Pierre Sourdille3, Arnaud Couloux2, Etienne Paux3, Philippe Leroy3, Sophie Mangenot2, Nicolas Guilhot3, Jacques Le Gouis3, Francois Balfourier3, Michael Alaux4, Véronique Jamilloux4, Julie Poulain2, Céline Durand2, Arnaud Bellec5, Christine Gaspin6, Jan Safar7, Jaroslav Dolezel7, Jane Rogers8, Klaas Vandepoele9, Jean-Marc Aury2, Klaus Mayer10, Hélène Berges5, Hadi Quesneville4, Patrick Wincker11, Catherine Feuillet3.
Abstract
We produced a reference sequence of the 1-gigabase chromosome 3B of hexaploid bread wheat. By sequencing 8452 bacterial artificial chromosomes in pools, we assembled a sequence of 774 megabases carrying 5326 protein-coding genes, 1938 pseudogenes, and 85% of transposable elements. The distribution of structural and functional features along the chromosome revealed partitioning correlated with meiotic recombination. Comparative analyses indicated high wheat-specific inter- and intrachromosomal gene duplication activities that are potential sources of variability for adaption. In addition to providing a better understanding of the organization, function, and evolution of a large and polyploid genome, the availability of a high-quality sequence anchored to genetic maps will accelerate the identification of genes underlying important agronomic traits.Entities:
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Year: 2014 PMID： 25035497 DOI： 10.1126/science.1249721
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728