Literature DB >> 25027652

Plant biology informs drug discovery.

Michael Rape1.   

Abstract

Michael Rape provides a striking example of how basic research — in this case in the plant sciences — can be unexpectedly informative for drug development.

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Year:  2014        PMID： 25027652     DOI： 10.1038/nrm3842

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  5 in total

1.  The F-box protein TIR1 is an auxin receptor.

Authors:  Nihal Dharmasiri; Sunethra Dharmasiri; Mark Estelle
Journal:  Nature       Date:  2005-05-26       Impact factor: 49.962

2.  Mechanism of auxin perception by the TIR1 ubiquitin ligase.

Authors:  Xu Tan; Luz Irina A Calderon-Villalobos; Michal Sharon; Changxue Zheng; Carol V Robinson; Mark Estelle; Ning Zheng
Journal:  Nature       Date:  2007-04-05       Impact factor: 49.962

3.  Identification of a primary target of thalidomide teratogenicity.

Authors:  Takumi Ito; Hideki Ando; Takayuki Suzuki; Toshihiko Ogura; Kentaro Hotta; Yoshimasa Imamura; Yuki Yamaguchi; Hiroshi Handa
Journal:  Science       Date:  2010-03-12       Impact factor: 47.728

4.  Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells.

Authors:  Jan Krönke; Namrata D Udeshi; Anupama Narla; Peter Grauman; Slater N Hurst; Marie McConkey; Tanya Svinkina; Dirk Heckl; Eamon Comer; Xiaoyu Li; Christie Ciarlo; Emily Hartman; Nikhil Munshi; Monica Schenone; Stuart L Schreiber; Steven A Carr; Benjamin L Ebert
Journal:  Science       Date:  2013-11-29       Impact factor: 47.728

5.  The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins.

Authors:  Gang Lu; Richard E Middleton; Huahang Sun; MarkVic Naniong; Christopher J Ott; Constantine S Mitsiades; Kwok-Kin Wong; James E Bradner; William G Kaelin
Journal:  Science       Date:  2013-11-29       Impact factor: 47.728
  5 in total
  1 in total

1.  Exploring the catalytic function and active sites of a novel C-glycosyltransferase from Anemarrhena asphodeloides.

Authors:  Jia Huang; Yaru She; Jingyang Yue; Yidu Chen; Yu Li; Jing Li; Yonger Hu; Deying Yang; Jiabo Chen; Lu Yang; Zhongqiu Liu; Ruibo Wu; Pengfei Jin; Lixin Duan
Journal:  Synth Syst Biotechnol       Date:  2022-02-07
  1 in total

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