Literature DB >> 25016281

The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changes.

Tanya T Paull1, Rajashree A Deshpande2.   

Abstract

Entities:  

Keywords:  DNA double-strand break repair; Mre11; Nbs1; Rad50

Mesh：

Substances：

Year:  2014        PMID： 25016281      PMCID： PMC4252570          DOI： 10.1016/j.yexcr.2014.07.007

Source DB:  PubMed          Journal:  Exp Cell Res        ISSN： 0014-4827            Impact factor:   3.905


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  96 in total

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3.  The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder.

Authors:  G S Stewart; R S Maser; T Stankovic; D A Bressan; M I Kaplan; N G Jaspers; A Raams; P J Byrd; J H Petrini; A M Taylor
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Review 4.  The MRN complex in double-strand break repair and telomere maintenance.

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Journal:  FEBS Lett       Date:  2010-07-24       Impact factor: 4.124

Review 5.  Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae.

Authors:  L K Lewis; M A Resnick
Journal:  Mutat Res       Date:  2000-06-30       Impact factor: 2.433

6.  53BP1 promotes ATM activity through direct interactions with the MRN complex.

Authors:  Ji-Hoon Lee; Aaron A Goodarzi; Penny A Jeggo; Tanya T Paull
Journal:  EMBO J       Date:  2009-12-10       Impact factor: 11.598

7.  Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder.

Authors:  Regina Waltes; Reinhard Kalb; Magtouf Gatei; Amanda W Kijas; Markus Stumm; Alexandra Sobeck; Britta Wieland; Raymonda Varon; Yaniv Lerenthal; Martin F Lavin; Detlev Schindler; Thilo Dörk
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8.  N terminus of CtIP is critical for homologous recombination-mediated double-strand break repair.

Authors:  Jingsong Yuan; Junjie Chen
Journal:  J Biol Chem       Date:  2009-09-16       Impact factor: 5.157

9.  Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.

Authors:  R Scott Williams; Gerald E Dodson; Oliver Limbo; Yoshiki Yamada; Jessica S Williams; Grant Guenther; Scott Classen; J N Mark Glover; Hiroshi Iwasaki; Paul Russell; John A Tainer
Journal:  Cell       Date:  2009-10-02       Impact factor: 41.582

10.  CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

Authors:  Maximina H Yun; Kevin Hiom
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1.  A universal fluorescence-based toolkit for real-time quantification of DNA and RNA nuclease activity.

Authors:  Emily C Sheppard; Sally Rogers; Nicholas J Harmer; Richard Chahwan
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3.  Evaluation of miRNA-binding-site SNPs of MRE11A, NBS1, RAD51 and RAD52 involved in HRR pathway genes and risk of breast cancer in China.

Authors:  Zhenzhen Wu; Peng Wang; Chunhua Song; Kaijuan Wang; Rui Yan; Jingruo Li; Liping Dai
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Review 4.  Eukaryotic resectosomes: A single-molecule perspective.

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5.  A network of allosterically coupled residues in the bacteriophage T4 Mre11-Rad50 complex.

Authors:  Yang Gao; Jennifer R Meyer; Scott W Nelson
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6.  Purification and Biophysical Characterization of the Mre11-Rad50-Nbs1 Complex.

Authors:  Logan R Myler; Michael M Soniat; Xiaoming Zhang; Rajashree A Deshpande; Tanya T Paull; Ilya J Finkelstein
Journal:  Methods Mol Biol       Date:  2019

7.  Interdependent and separable functions of Caenorhabditis elegans MRN-C complex members couple formation and repair of meiotic DSBs.

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Review 8.  Sharpening the ends for repair: mechanisms and regulation of DNA resection.

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Review 9.  The Role of Nucleic Acid Sensing in Controlling Microbial and Autoimmune Disorders.

Authors:  Keesha M Matz; R Marena Guzman; Alan G Goodman
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Review 10.  Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair.

Authors:  Julien Lafrance-Vanasse; Gareth J Williams; John A Tainer
Journal:  Prog Biophys Mol Biol       Date:  2015-01-07       Impact factor: 3.667
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