Literature DB >> 25012592

A bioorthogonal (68)Ga-labelling strategy for rapid in vivo imaging.

Helen L Evans1, Quang-Dé Nguyen, Laurence S Carroll, Maciej Kaliszczak, Frazer J Twyman, Alan C Spivey, Eric O Aboagye.   

Abstract

Herein, we describe a fast and robust method for achieving (68)Ga-labelling of the EGFR-selective monoclonal antibody (mAb) Cetuximab using the bioorthogonal Inverse-electron-Demand Diels-Alder (IeDDA) reaction. The in vivo imaging of EGFR is demonstrated, as well as the translation of the method within a two-step pretargeting strategy.

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Year:  2014        PMID： 25012592     DOI： 10.1039/c4cc03903c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  18 in total

Review 1.  Click Reaction: An Applicable Radiolabeling Method for Molecular Imaging.

Authors:  Ji Young Choi; Byung Chul Lee
Journal:  Nucl Med Mol Imaging       Date:  2015-10-19

Review 2.  In vivo imaging with antibodies and engineered fragments.

Authors:  Amanda C Freise; Anna M Wu
Journal:  Mol Immunol       Date:  2015-04-28       Impact factor: 4.407

Review 3.  Radiopharmaceuticals as probes to characterize tumour tissue.

Authors:  Israt S Alam; Mubarik A Arshad; Quang-Dé Nguyen; Eric O Aboagye
Journal:  Eur J Nucl Med Mol Imaging       Date:  2015-02-03       Impact factor: 9.236

Review 4.  Click Chemistry and Radiochemistry: The First 10 Years.

Authors:  Jan-Philip Meyer; Pierre Adumeau; Jason S Lewis; Brian M Zeglis
Journal:  Bioconjug Chem       Date:  2016-11-22       Impact factor: 4.774

5.  89Zr-DFO-Cetuximab as a Molecular Imaging Agent to Identify Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma.

Authors:  Raquel Benedetto; Adriana V F Massicano; Bryant K Crenshaw; Renato Oliveira; Rui M Reis; Elaine B Araújo; Suzanne E Lapi
Journal:  Cancer Biother Radiopharm       Date:  2019-03-13       Impact factor: 3.099

6.  Optimization of Direct Aromatic 18F-Labeling of Tetrazines.

Authors:  Ida Vang Andersen; Rocío García-Vázquez; Umberto Maria Battisti; Matthias M Herth
Journal:  Molecules       Date:  2022-06-22       Impact factor: 4.927

Review 7.  Recent Advances in the Development of Tetrazine Ligation Tools for Pretargeted Nuclear Imaging.

Authors:  Rocío García-Vázquez; Umberto Maria Battisti; Matthias M Herth
Journal:  Pharmaceuticals (Basel)       Date:  2022-05-30

8.  Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics.

Authors:  Brian M Zeglis; Christian Brand; Dalya Abdel-Atti; Kathryn E Carnazza; Brendon E Cook; Sean Carlin; Thomas Reiner; Jason S Lewis
Journal:  Mol Pharm       Date:  2015-08-31       Impact factor: 4.939

9.  Exploring Structural Parameters for Pretargeting Radioligand Optimization.

Authors:  Jan-Philip Meyer; Paul Kozlowski; James Jackson; Kristen M Cunanan; Pierre Adumeau; Thomas R Dilling; Brian M Zeglis; Jason S Lewis
Journal:  J Med Chem       Date:  2017-09-20       Impact factor: 7.446

10.  Detecting hypoxia in vitro using 18F-pretargeted IEDDA "click" chemistry in live cells.

Authors:  Louis Allott; Cen Chen; Marta Braga; Sau Fung Jacob Leung; Ning Wang; Chris Barnes; Diana Brickute; Laurence Carroll; Eric O Aboagye
Journal:  RSC Adv       Date:  2021-06-07       Impact factor: 4.036
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