Literature DB >> 25011544

Long-lasting changes in brain activation induced by a single REAC technology pulse in Wi-Fi bands. Randomized double-blind fMRI qualitative study.

Salvatore Rinaldi1, Marco Mura2, Alessandro Castagna1, Vania Fontani1.   

Abstract

The aim of this randomized double-blind study was to evaluate in healthy adult subjects, with functional magnetic resonance imaging (fMRI), long lasting changes in brain activation patterns following administration of a single, 250 milliseconds pulse emitted with radio-electric asymmetric conveyer (REAC) technology in the Wi-Fi bands. The REAC impulse was not administered during the scan, but after this, according to a protocol that has previously been demonstrated to be effective in improving motor control and postural balance, in healthy subjects and patients. The study was conducted on 33 healthy volunteers, performed with a 1.5 T unit while operating a motor block task involving cyclical and alternating flexion and extension of one leg. Subsequently subjects were randomly divided into a treatment and a sham treatment control group. Repeated fMRI examinations were performed following the administration of the REAC pulse or sham treatment. The Treated group showed cerebellar and ponto-mesencephalic activation components that disappeared in the second scan, while these activation components persisted in the Sham group. This study shows that a very weak signal, such as 250 milliseconds Wi-Fi pulse, administered with REAC technology, could lead to lasting effects on brain activity modification.

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Year:  2014        PMID: 25011544      PMCID: PMC4092330          DOI: 10.1038/srep05668

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  21 in total

1.  Dorsal posterior parietal rTMS affects voluntary orienting of visuospatial attention.

Authors:  Gregor Thut; Annika Nietzel; Alvaro Pascual-Leone
Journal:  Cereb Cortex       Date:  2004-09-01       Impact factor: 5.357

2.  Motor effects of REAC in advanced Alzheimer's disease: results from a pilot trial.

Authors:  Javier Olazarán; Belén González; Jorge López-Álvarez; Alessandro Castagna; Emma Osa-Ruiz; Vanesa Herrero-Cano; Luis Agüera-Ortiz; Salvatore Rinaldi; Pablo Martínez-Martín
Journal:  J Alzheimers Dis       Date:  2013       Impact factor: 4.472

3.  Biophysical foundations underlying TMS: setting the stage for an effective use of neurostimulation in the cognitive neurosciences.

Authors:  Tim Wagner; Jarrett Rushmore; Uri Eden; Antoni Valero-Cabre
Journal:  Cortex       Date:  2008-10-22       Impact factor: 4.027

4.  Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor.

Authors:  Piero Mannu; Salvatore Rinaldi; Vania Fontani; Alessandro Castagna
Journal:  Neuropsychiatr Dis Treat       Date:  2011-06-15       Impact factor: 2.570

5.  Stress-related psycho-physiological disorders: randomized single blind placebo controlled naturalistic study of psychometric evaluation using a radio electric asymmetric treatment.

Authors:  Salvatore Rinaldi; Vania Fontani; Lucia Aravagli; Piero Mannu; Alessandro Castagna; Matteo Lotti Margotti; Barbara Rosettani
Journal:  Health Qual Life Outcomes       Date:  2011-07-19       Impact factor: 3.186

6.  Radio electric asymmetric brain stimulation in the treatment of behavioral and psychiatric symptoms in Alzheimer disease.

Authors:  Piero Mannu; Salvatore Rinaldi; Vania Fontani; Alessandro Castagna
Journal:  Clin Interv Aging       Date:  2011-07-26       Impact factor: 4.458

7.  Noninvasive brain stimulation by radioelectric asymmetric conveyor in the treatment of agoraphobia: open-label, naturalistic study.

Authors:  Piero Mannu; Salvatore Rinaldi; Vania Fontani; Alessandro Castagna; Matteo Lotti Margotti
Journal:  Patient Prefer Adherence       Date:  2011-11-18       Impact factor: 2.711

8.  Noninvasive radioelectric asymmetric conveyor brain stimulation treatment improves balance in individuals over 65 suffering from neurological diseases: pilot study.

Authors:  Vania Fontani; Salvatore Rinaldi; Alessandro Castagna; Matteo Lotti Margotti
Journal:  Ther Clin Risk Manag       Date:  2012-02-17       Impact factor: 2.423

9.  Social anxiety disorder: radio electric asymmetric conveyor brain stimulation versus sertraline.

Authors:  Vania Fontani; Piero Mannu; Alessandro Castagna; Salvatore Rinaldi
Journal:  Patient Prefer Adherence       Date:  2011-11-22       Impact factor: 2.711

10.  Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria.

Authors:  Marco Mura; Alessandro Castagna; Vania Fontani; Salvatore Rinaldi
Journal:  Neuropsychiatr Dis Treat       Date:  2012-04-04       Impact factor: 2.570

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  17 in total

1.  Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a Mouse Model of Neurodegeneration.

Authors:  Maria Antonietta Panaro; Alessandra Aloisi; Giuseppe Nicolardi; Dario Domenico Lofrumento; Francesco De Nuccio; Velia La Pesa; Antonia Cianciulli; Rosaria Rinaldi; Rosa Calvello; Vania Fontani; Salvatore Rinaldi
Journal:  Neurosci Bull       Date:  2017-11-10       Impact factor: 5.203

2.  Radio Electric Asymmetric Conveyer (REAC) Neurobiological Stimulation Treatments in Dysfunctional Motor Behavior in Flail Arm Syndrome: A Case Report.

Authors:  Salvatore Rinaldi; Chiara Rinaldi; Arianna Rinaldi; Vania Fontani
Journal:  Cureus       Date:  2022-08-19

3.  Regenerative Radio Electric Asymmetric Conveyer Treatment in Generalized Cerebral and Cerebellar Atrophy to Improve Motor Control: A Case Report.

Authors:  Salvatore Rinaldi; Chiara Rinaldi; Vania Fontani
Journal:  Cureus       Date:  2022-08-21

4.  Calcific Tendinitis of the Shoulder: A Neuro-Psychomotor Behavioral Diagnostic and Therapeutic Approach With Radioelectric Asymmetric Conveyer Neurobiological Stimulation Treatments.

Authors:  Vania Fontani; Arianna Rinaldi; Alessandro Castagna; Salvatore Rinaldi
Journal:  Cureus       Date:  2022-07-12

5.  Neuro Postural Optimization Neuromodulation Treatment of Radio Electric Asymmetric Conveyer Technology on Stress and Quality of Life in Institutionalized Children in a Capital City of the Brazilian Amazon.

Authors:  Ana V Gonçalves de Oliveira Cruz; Rebeca Góes Gonçalves; Lucas Nunes; João Douglas Quaresma de Oliveira; Ester S Lima Monteiro; Italo Soares Eneias; Taynara C Guilherme Lima; Larissa Duarte Ferreira; Erick Souza Neri; José L da Cunha Pena; Anelli M Célis de Cárdenas; Maria I Côrtes Volpe; Maria V Filgueiras de Assis Melo; Arianna Rinaldi; Ana R Pinheiro Barcessat
Journal:  Cureus       Date:  2022-07-04

6.  Electrophysiological effects of non-invasive Radio Electric Asymmetric Conveyor (REAC) on thalamocortical neural activities and perturbed experimental conditions.

Authors:  Antonio G Zippo; Salvatore Rinaldi; Giulio Pellegata; Gian Carlo Caramenti; Maurizio Valente; Vania Fontani; Gabriele E M Biella
Journal:  Sci Rep       Date:  2015-12-11       Impact factor: 4.379

Review 7.  Radio electric asymmetric conveyer: a novel neuromodulation technology in Alzheimer's and other neurodegenerative diseases.

Authors:  Salvatore Rinaldi; Laura Calzà; Luciana Giardino; Gabriele E M Biella; Antonio G Zippo; Vania Fontani
Journal:  Front Psychiatry       Date:  2015-02-17       Impact factor: 4.157

8.  REAC technology modifies pathological neuroinflammation and motor behaviour in an Alzheimer's disease mouse model.

Authors:  Luca Lorenzini; Alessandro Giuliani; Sandra Sivilia; Mercedes Fernandez; Matteo Lotti Margotti; Luciana Giardino; Vania Fontani; Salvatore Rinaldi
Journal:  Sci Rep       Date:  2016-10-24       Impact factor: 4.379

9.  REAC regenerative treatment efficacy in experimental chondral lesions: a pilot study on ovine animal model.

Authors:  Eraldo Sanna Passino; Stefano Rocca; Sabrina Caggiu; Nicolò Columbano; Alessandro Castagna; Vania Fontani; Salvatore Rinaldi
Journal:  Clin Interv Aging       Date:  2017-09-14       Impact factor: 4.458

10.  REAC neuromodulation treatments in subjects with severe socioeconomic and cultural hardship in the Brazilian state of Pará: a family observational pilot study.

Authors:  José Alfredo Coelho Pereira; Arianna Rinaldi; Vania Fontani; Salvatore Rinaldi
Journal:  Neuropsychiatr Dis Treat       Date:  2018-04-16       Impact factor: 2.570

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