Literature DB >> 36039125

Regenerative Radio Electric Asymmetric Conveyer Treatment in Generalized Cerebral and Cerebellar Atrophy to Improve Motor Control: A Case Report.

Salvatore Rinaldi1,2, Chiara Rinaldi3, Vania Fontani1,2.   

Abstract

This report presents a case with a diagnosis rarely described in the literature, that is generalized cerebral-cerebellar atrophy. The patient showed a rapid decline with general cognitive deterioration, memory loss, temporal and spatial disorientation, and ataxic manifestations in voluntary movements. The loss of neurons and synaptic connections can be explained by an alteration of the correct endogenous bioelectrical activity (EBA), the phenomenon which allows all the processes of cellular life, such as differentiation, proliferation, migration, morphogenesis, apoptosis, and neurotransmission. The patient was treated with a specific regenerative neurobiological stimulation treatment applied with the radio electric asymmetric conveyer (REAC) technology, which was designed to recover the correct EBA. The tissue optimization regenerative (TO RGN) treatments used in this case report have already demonstrated the ability to induce neuroregenerative processes. At the follow-up, the patient showed a reduction in ataxia both in walking and running. This case report allows us to learn that the manipulation of the EBA can induce improvements even in clinical cases in which the scientific literature leaves no room for improvement.
Copyright © 2022, Rinaldi et al.

Entities:  

Keywords:  cerebellar atrophy; cerebral atrophy; endogenous bioelectrical activity; endogenous bioelectrical fields; neurobiological stimulation; neuromodulation; neurostimulation; reac

Year:  2022        PMID: 36039125      PMCID: PMC9396963          DOI: 10.7759/cureus.28245

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  16 in total

1.  Endogenous gradients of resting potential instructively pattern embryonic neural tissue via Notch signaling and regulation of proliferation.

Authors:  Vaibhav P Pai; Joan M Lemire; Jean-François Paré; Gufa Lin; Ying Chen; Michael Levin
Journal:  J Neurosci       Date:  2015-03-11       Impact factor: 6.167

Review 2.  Endogenous Bioelectric Signaling Networks: Exploiting Voltage Gradients for Control of Growth and Form.

Authors:  Michael Levin; Giovanni Pezzulo; Joshua M Finkelstein
Journal:  Annu Rev Biomed Eng       Date:  2017-06-21       Impact factor: 9.590

Review 3.  Endogenous bioelectrical networks store non-genetic patterning information during development and regeneration.

Authors:  Michael Levin
Journal:  J Physiol       Date:  2014-06-01       Impact factor: 5.182

Review 4.  Endogenous voltage gradients as mediators of cell-cell communication: strategies for investigating bioelectrical signals during pattern formation.

Authors:  Dany S Adams; Michael Levin
Journal:  Cell Tissue Res       Date:  2012-02-17       Impact factor: 5.249

5.  Antisenescence effect of REAC biomodulation to counteract the evolution of myelodysplastic syndrome.

Authors:  M Maioli; S Rinaldi; S Cruciani; A Necas; V Fontani; G Corda; S Santaniello; A Rinaldi; Arp Barcessat; A Necasova; A Castagna; Z Filipejova; C Ventura; C Fozza
Journal:  Physiol Res       Date:  2022-07-28       Impact factor: 2.139

6.  Radioelectric asymmetric conveyed fields and human adipose-derived stem cells obtained with a nonenzymatic method and device: a novel approach to multipotency.

Authors:  Margherita Maioli; Salvatore Rinaldi; Sara Santaniello; Alessandro Castagna; Gianfranco Pigliaru; Alessandro Delitala; Francesca Bianchi; Carlo Tremolada; Vania Fontani; Carlo Ventura
Journal:  Cell Transplant       Date:  2013-08-30       Impact factor: 4.064

7.  Brain activity modification produced by a single radioelectric asymmetric brain stimulation pulse: a new tool for neuropsychiatric treatments. Preliminary fMRI study.

Authors:  Salvatore Rinaldi; Vania Fontani; Alessandro Castagna
Journal:  Neuropsychiatr Dis Treat       Date:  2011-10-28       Impact factor: 2.570

8.  Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria.

Authors:  Marco Mura; Alessandro Castagna; Vania Fontani; Salvatore Rinaldi
Journal:  Neuropsychiatr Dis Treat       Date:  2012-04-04       Impact factor: 2.570

9.  Neurological morphofunctional differentiation induced by REAC technology in PC12. A neuro protective model for Parkinson's disease.

Authors:  Margherita Maioli; Salvatore Rinaldi; Rossana Migheli; Gianfranco Pigliaru; Gaia Rocchitta; Sara Santaniello; Valentina Basoli; Alessandro Castagna; Vania Fontani; Carlo Ventura; Pier Andrea Serra
Journal:  Sci Rep       Date:  2015-05-15       Impact factor: 4.379

10.  REAC technology modifies pathological neuroinflammation and motor behaviour in an Alzheimer's disease mouse model.

Authors:  Luca Lorenzini; Alessandro Giuliani; Sandra Sivilia; Mercedes Fernandez; Matteo Lotti Margotti; Luciana Giardino; Vania Fontani; Salvatore Rinaldi
Journal:  Sci Rep       Date:  2016-10-24       Impact factor: 4.379

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