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Literature DB >> 25006435

Epigenetic modifications: basic mechanisms and role in cardiovascular disease (2013 Grover Conference series).

Abstract

Epigenetics refers to heritable traits that are not a consequence of DNA sequence. Three classes of epigenetic regulation exist: DNA methylation, histone modification, and noncoding RNA action. In the cardiovascular system, epigenetic regulation affects development, differentiation, and disease propensity or expression. Defining the determinants of epigenetic regulation offers opportunities for novel strategies for disease prevention and treatment.

Entities: Disease

Keywords: atherosclerosis; histone; homocysteine; methylation; noncoding RNAs; pulmonary hypertension

Year: 2014 PMID： 25006435 PMCID： PMC4070783 DOI： 10.1086/675979

Source DB: PubMed Journal: Pulm Circ ISSN： 2045-8932 Impact factor: 3.017

52 in total

1. Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc.

Authors: Cuk-Seong Kim; Young-Rae Kim; Asma Naqvi; Santosh Kumar; Timothy A Hoffman; Saet-Byel Jung; Ajay Kumar; Byeong-Hwa Jeon; Dennis M McNamara; Kaikobad Irani
Journal: Cardiovasc Res Date: 2011-09-20 Impact factor: 10.787

Review 2. Epigenetic modifications of stem cells: a paradigm for the control of cardiac progenitor cells.

Authors: Yonggang Zhou; Johnny Kim; Xuejun Yuan; Thomas Braun
Journal: Circ Res Date: 2011-10-14 Impact factor: 17.367

3. Histone demethylation by a family of JmjC domain-containing proteins.

Authors: Yu-ichi Tsukada; Jia Fang; Hediye Erdjument-Bromage; Maria E Warren; Christoph H Borchers; Paul Tempst; Yi Zhang
Journal: Nature Date: 2005-12-18 Impact factor: 49.962

Review 4. RNA nucleotide methylation.

Authors: Yuri Motorin; Mark Helm
Journal: Wiley Interdiscip Rev RNA Date: 2011-03-23 Impact factor: 9.957

5. A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples.

Authors: Paola Caruso; Yvonne Dempsie; Hannah C Stevens; Robert A McDonald; Lu Long; Ruifang Lu; Kevin White; Kirsty M Mair; John D McClure; Mark Southwood; Paul Upton; Mei Xin; Eva van Rooij; Eric N Olson; Nicholas W Morrell; Margaret R MacLean; Andrew H Baker
Journal: Circ Res Date: 2012-06-19 Impact factor: 17.367

6. Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation.

Authors: P Yi; S Melnyk; M Pogribna; I P Pogribny; R J Hine; S J James
Journal: J Biol Chem Date: 2000-09-22 Impact factor: 5.157

Review 7. The role of redox signaling in epigenetics and cardiovascular disease.

Authors: Gene H Kim; John J Ryan; Stephen L Archer
Journal: Antioxid Redox Signal Date: 2013-03-12 Impact factor: 8.401

Review 8. Sirtuins in mammals: insights into their biological function.

Authors: Shaday Michan; David Sinclair
Journal: Biochem J Date: 2007-05-15 Impact factor: 3.857

Review 9. Tet family proteins and 5-hydroxymethylcytosine in development and disease.

Authors: Li Tan; Yujiang Geno Shi
Journal: Development Date: 2012-06 Impact factor: 6.868

10. Role for miR-204 in human pulmonary arterial hypertension.

Authors: Audrey Courboulin; Roxane Paulin; Nellie J Giguère; Nehmé Saksouk; Tanya Perreault; Jolyane Meloche; Eric R Paquet; Sabrina Biardel; Steeve Provencher; Jacques Côté; Martin J Simard; Sébastien Bonnet
Journal: J Exp Med Date: 2011-02-14 Impact factor: 14.307

44 in total

1. Lysine-Specific Demethylase-1 Deficiency Increases Agonist Signaling Via the Mineralocorticoid Receptor.

Authors: Thitinan Treesaranuwattana; Kelly Yin Han Wong; Danielle L Brooks; Chee Sin Tay; Gordon H Williams; Jonathan S Williams; Luminita H Pojoga
Journal: Hypertension Date: 2020-03-11 Impact factor: 10.190

2. Subchronic methionine load induces oxidative stress and provokes biochemical and histological changes in the rat liver tissue.

Authors: M Stojanović; D Todorović; Lj Šćepanović; D Mitrović; S Borozan; V Dragutinović; M Labudović-Borović; D Krstić; M Čolović; D Djuric
Journal: Mol Cell Biochem Date: 2018-02-08 Impact factor: 3.396

3. Oroxylin A, a natural anticancer flavonoid compound, induces differentiation of t(8;21)-positive Kasumi-1 and primary acute myeloid leukemia cells.

Authors: Hui Hui; Xiaoxiao Zhang; Hui Li; Xiao Liu; Le Shen; Yu Zhu; Jingyan Xu; Qinglong Guo; Na Lu
Journal: J Cancer Res Clin Oncol Date: 2016-04-16 Impact factor: 4.553

4. Genome-wide identification of long noncoding RNAs in rat models of cardiovascular and renal disease.

Authors: Kathirvel Gopalakrishnan; Sivarajan Kumarasamy; Blair Mell; Bina Joe
Journal: Hypertension Date: 2014-11-10 Impact factor: 10.190

Review 5. Epigenetic Inheritance Underlying Pulmonary Arterial Hypertension.

Authors: Claudio Napoli; Giuditta Benincasa; Joseph Loscalzo
Journal: Arterioscler Thromb Vasc Biol Date: 2019-04 Impact factor: 8.311

6. Quantitative DNA methylation analysis of paired box gene 1 and LIM homeobox transcription factor 1 α genes in cervical cancer.

Authors: Ling Xu; Jun Xu; Zheng Hu; Baohua Yang; Lifeng Wang; Xiao Lin; Ziyin Xia; Zhiling Zhang; Yunheng Zhu
Journal: Oncol Lett Date: 2018-01-26 Impact factor: 2.967

Review 7. Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems.

Authors: Tarek Magdy; Adam J T Schuldt; Joseph C Wu; Daniel Bernstein; Paul W Burridge
Journal: Annu Rev Pharmacol Toxicol Date: 2017-10-06 Impact factor: 13.820