Literature DB >> 25005482

Mobile DNA elements in the generation of diversity and complexity in the brain.

Jennifer A Erwin1, Maria C Marchetto1, Fred H Gage1.   

Abstract

Mobile elements are DNA sequences that can change their position (retrotranspose) within the genome. Although its biological function is largely unappreciated, DNA derived from mobile elements comprises nearly half of the human genome. It has long been thought that neuronal genomes are invariable; however, recent studies have demonstrated that mobile elements actively retrotranspose during neurogenesis, thereby creating genomic diversity between neurons. In addition, mounting data demonstrate that mobile elements are misregulated in certain neurological disorders, including Rett syndrome and schizophrenia.

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Year:  2014        PMID： 25005482      PMCID： PMC4443810          DOI： 10.1038/nrn3730

Source DB:  PubMed          Journal:  Nat Rev Neurosci        ISSN： 1471-003X            Impact factor:   34.870


  79 in total

1.  Retrotransposition of marked SVA elements by human L1s in cultured cells.

Authors:  Dustin C Hancks; John L Goodier; Prabhat K Mandal; Ling E Cheung; Haig H Kazazian
Journal:  Hum Mol Genet       Date:  2011-06-02       Impact factor: 6.150

2.  Genomic deletions created upon LINE-1 retrotransposition.

Authors:  Nicolas Gilbert; Sheila Lutz-Prigge; John V Moran
Journal:  Cell       Date:  2002-08-09       Impact factor: 41.582

3.  Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence.

Authors:  Igor Ponomarev; Shi Wang; Lingling Zhang; R Adron Harris; R Dayne Mayfield
Journal:  J Neurosci       Date:  2012-02-01       Impact factor: 6.167

4.  The significance of responses of the genome to challenge.

Authors:  B McClintock
Journal:  Science       Date:  1984-11-16       Impact factor: 47.728

5.  Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition.

Authors:  Q Feng; J V Moran; H H Kazazian; J D Boeke
Journal:  Cell       Date:  1996-11-29       Impact factor: 41.582

6.  Novel PAX6 binding sites in the human genome and the role of repetitive elements in the evolution of gene regulation.

Authors:  Yi-Hong Zhou; Jessica B Zheng; Xun Gu; Grady F Saunders; W-K Alfred Yung
Journal:  Genome Res       Date:  2002-11       Impact factor: 9.043

7.  LINE-mediated retrotransposition of marked Alu sequences.

Authors:  Marie Dewannieux; Cécile Esnault; Thierry Heidmann
Journal:  Nat Genet       Date:  2003-08-03       Impact factor: 38.330

8.  Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice.

Authors:  Daniela Tropea; Emanuela Giacometti; Nathan R Wilson; Caroline Beard; Cortina McCurry; Dong Dong Fu; Ruth Flannery; Rudolf Jaenisch; Mriganka Sur
Journal:  Proc Natl Acad Sci U S A       Date:  2009-02-10       Impact factor: 11.205

Review 9.  The role of MeCP2 in the brain.

Authors:  Jacky Guy; Hélène Cheval; Jim Selfridge; Adrian Bird
Journal:  Annu Rev Cell Dev Biol       Date:  2011-06-29       Impact factor: 13.827

Review 10.  Epigenetic control of gene expression in the alcoholic brain.

Authors:  Igor Ponomarev
Journal:  Alcohol Res       Date:  2013
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  121 in total

1.  Neuroepigenomics: Resources, Obstacles, and Opportunities.

Authors:  John S Satterlee; Andrea Beckel-Mitchener; Roger Little; Dena Procaccini; Joni L Rutter; Amy C Lossie
Journal:  Neuroepigenetics       Date:  2015-01-01

2.  Epigenetic changes in the developing brain: Effects on behavior.

Authors:  Eric B Keverne; Donald W Pfaff; Inna Tabansky
Journal:  Proc Natl Acad Sci U S A       Date:  2015-06-02       Impact factor: 11.205

Review 3.  Stress and the dynamic genome: Steroids, epigenetics, and the transposome.

Authors:  Richard G Hunter; Khatuna Gagnidze; Bruce S McEwen; Donald W Pfaff
Journal:  Proc Natl Acad Sci U S A       Date:  2014-11-10       Impact factor: 11.205

4.  Detainment of Tam3 Transposase at Plasma Membrane by Its BED-Zinc Finger Domain.

Authors:  Hua Zhou; Megumi Hirata; Ryo Osawa; Kaien Fujino; Yuji Kishima
Journal:  Plant Physiol       Date:  2016-12-22       Impact factor: 8.340

5.  Engrailed homeoprotein blocks degeneration in adult dopaminergic neurons through LINE-1 repression.

Authors:  François-Xavier Blaudin de Thé; Hocine Rekaik; Eugenie Peze-Heidsieck; Olivia Massiani-Beaudoin; Rajiv L Joshi; Julia Fuchs; Alain Prochiantz
Journal:  EMBO J       Date:  2018-06-25       Impact factor: 11.598

Review 6.  Extracellular vesicles and intercellular communication within the nervous system.

Authors:  Valentina Zappulli; Kristina Pagh Friis; Zachary Fitzpatrick; Casey A Maguire; Xandra O Breakefield
Journal:  J Clin Invest       Date:  2016-04-01       Impact factor: 14.808

7.  Transposable elements and miRNA: Regulation of genomic stability and plasticity.

Authors:  Irene Munk Pedersen; Dimitrios G Zisoulis
Journal:  Mob Genet Elements       Date:  2016-04-08

Review 8.  Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use.

Authors:  John F Atkins; Gary Loughran; Pramod R Bhatt; Andrew E Firth; Pavel V Baranov
Journal:  Nucleic Acids Res       Date:  2016-07-19       Impact factor: 16.971

Review 9.  Somatic mosaicism: implications for disease and transmission genetics.

Authors:  Ian M Campbell; Chad A Shaw; Pawel Stankiewicz; James R Lupski
Journal:  Trends Genet       Date:  2015-04-21       Impact factor: 11.639

Review 10.  Surprising origins of sex differences in the brain.

Authors:  Margaret M McCarthy; Lindsay A Pickett; Jonathan W VanRyzin; Katherine E Kight
Journal:  Horm Behav       Date:  2015-04-25       Impact factor: 3.587
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