Rudolf Metelka1. 1. Department of Internal Medicine III - Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic.
Abstract
BACKROUND: The autonomic nervous system is one of the major homeostatic regulatory systems of the body. Detection of cardiac autonomic neuropathy (CAN), reflected by reduced heart rate variability (HRV), is an independent adverse prognostic factor: sympathovagal balance failure with a sympathetic dominance is the main trigger for lethal arrhythmias and sudden death. METHODS AND RESULTS: PubMed database based on original articles from 1983 to 2013 and the author´s clinical experience. This review covers the current status of the methodology and the clinical uses of HRV, especially in the field of internal medicine. CONCLUSION: Heart rate variability is making a valuable contribution to the diagnosis of cardiovascular autonomic dysfunction and CAN. It can be assessed from short-term and long-term ECG recordings. It is one of the few methods that allow outpatient CAN diagnosis, monitoring the progress, therapeutic effect and evaluation of patient prognosis. It is used as an independent prognostic factor in combination with other recognized risk factors in risk stratifying after myocardial infarction. It is a unique method of CAN diagnosis particularly in diabetology. Its diagnostic and prognostic potential in other medical fields is being intensively explored.
BACKROUND: The autonomic nervous system is one of the major homeostatic regulatory systems of the body. Detection of cardiac autonomic neuropathy (CAN), reflected by reduced heart rate variability (HRV), is an independent adverse prognostic factor: sympathovagal balance failure with a sympathetic dominance is the main trigger for lethal arrhythmias and sudden death. METHODS AND RESULTS: PubMed database based on original articles from 1983 to 2013 and the author´s clinical experience. This review covers the current status of the methodology and the clinical uses of HRV, especially in the field of internal medicine. CONCLUSION: Heart rate variability is making a valuable contribution to the diagnosis of cardiovascular autonomic dysfunction and CAN. It can be assessed from short-term and long-term ECG recordings. It is one of the few methods that allow outpatient CAN diagnosis, monitoring the progress, therapeutic effect and evaluation of patient prognosis. It is used as an independent prognostic factor in combination with other recognized risk factors in risk stratifying after myocardial infarction. It is a unique method of CAN diagnosis particularly in diabetology. Its diagnostic and prognostic potential in other medical fields is being intensively explored.
Authors: Lindsey Christoffersen; Todd M Gibson; Ching-Hon Pui; Vijaya Joshi; Robyn E Partin; Daniel M Green; Jennifer Q Lanctot; Carrie R Howell; Daniel A Mulrooney; Gregory T Armstrong; Leslie L Robison; Melissa M Hudson; Kirsten K Ness Journal: Pediatr Blood Cancer Date: 2020-05-08 Impact factor: 3.167
Authors: Anaclara Michel-Chávez; Bruno Estañol; José Antonio Gien-López; Adriana Robles-Cabrera; María Elena Huitrado-Duarte; René Moreno-Morales; Brayans Becerra-Luna Journal: Arq Bras Cardiol Date: 2015-07-03 Impact factor: 2.000
Authors: Jayesh Dalpatbhai Solanki; Sanket D Basida; Hemant B Mehta; Sunil J Panjwani; Bhakti P Gadhavi; Pathik Patel Journal: J Family Med Prim Care Date: 2016 Apr-Jun
Authors: Vincent M Quinten; Matijs van Meurs; Maurits H Renes; Jack J M Ligtenberg; Jan C Ter Maaten Journal: BMJ Open Date: 2017-11-17 Impact factor: 2.692