Literature DB >> 2500412

Antibiotics from basidiomycetes. XXXI. Aleurodiscal: an antifungal sesterterpenoid from Aleurodiscus mirabilis (Berk. & Curt.) Höhn.

U Lauer1, T Anke, W S Sheldrick, A Scherer, W Steglich.   

Abstract

Aleurodiscal, an antifungal antibiotic has been isolated from mycelial cultures of Aleurodiscus mirabilis (Berk. & Curt.) Höhn. It causes abnormal apical branchings of Mucor miehei hyphae at very low concentrations. The structure and absolute configuration of the antibiotic has been determined by a single crystal X-ray analysis and hydrolysis to D-(+)-xylose. Aleurodiscal is a hydroxysesterterpene aldehyde beta-D-xyloside with a novel carbon skeleton.

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Year:  1989        PMID: 2500412     DOI: 10.7164/antibiotics.42.875

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  3 in total

1.  Evolution of a Unified Strategy for Complex Sesterterpenoids: Progress toward Astellatol and the Total Synthesis of (-)-Nitidasin.

Authors:  Daniel T Hog; Florian M E Huber; Gonzalo Jiménez-Osés; Peter Mayer; Kendall N Houk; Dirk Trauner
Journal:  Chemistry       Date:  2015-08-20       Impact factor: 5.236

2.  Biotransformation of 1,8-Dihydroxyanthraquinone into Peniphenone under the Fermentation of Aleurodiscus mirabilis.

Authors:  Ruifeng Mei; Yaxian Shi; Shengqi Zhang; Juntao Hu; Li Zhu; Junli Gan; Le Cai; Zhongtao Ding
Journal:  ACS Omega       Date:  2020-12-16

3.  Unearthing a sesterterpene biosynthetic repertoire in the Brassicaceae through genome mining reveals convergent evolution.

Authors:  Ancheng C Huang; Satria A Kautsar; Young J Hong; Marnix H Medema; Andrew D Bond; Dean J Tantillo; Anne Osbourn
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-03       Impact factor: 12.779

  3 in total

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