Literature DB >> 24999294

An Almost Linear Time Algorithm for Field Splitting in Radiation Therapy.

Xiaodong Wu1, Xin Dou2, John E Bayouth3, John M Buatti3.   

Abstract

In this paper, we study an interesting geometric partition problem, called optimal field splitting, which arises in Intensity-Modulated Radiation Therapy (IMRT). In current clinical practice, a multi-leaf collimator (MLC) with a maximum leaf spread constraint is used to deliver the prescribed intensity maps (IMs). However, the maximum leaf spread of an MLC may require to split a large intensity map into several overlapping sub-IMs with each being delivered separately. We develop a close-to-linear time algorithm for solving the field splitting problem while minimizing the total complexity of the resulting sub-IMs, thus improving the treatment delivery efficiency. Meanwhile, our algorithm strives to minimize the maximum beam-on time of those sub-IMs. Our basic idea is to formulate the field splitting problem as computing a shortest path in a directed acyclic graph, which expresses a special "layered" structure. The edge weights of the graph satisfy the Monge property, which enables us to solve this shortest path problem by examining only a small portion of the graph, yielding a close-to-linear time algorithm. To minimize the maximum beam-on time of the resulting sub-IMs, we consider an interesting min-max slope path problem in a monotone polygon which is solvable in linear time. The min-max slope path problem may be of interest in its own right. Experimental results based on real medical data and computer generated IMs showed that our new algorithm runs fast and produces high quality field splitting results.

Entities:  

Keywords:  IMRT field splitting; Monge property; algorithms; min-max slope paths; shortest paths

Year:  2013        PMID: 24999294      PMCID: PMC4078263          DOI: 10.1016/j.comgeo.2012.11.001

Source DB:  PubMed          Journal:  Comput Geom        ISSN: 0925-7721            Impact factor:   0.537


  4 in total

1.  Virtual micro-intensity modulated radiation therapy.

Authors:  R A Siochi
Journal:  Med Phys       Date:  2000-11       Impact factor: 4.071

2.  Dynamic splitting of large intensity-modulated fields.

Authors:  Q Wu; M Arnfield; S Tong; Y Wu; R Mohan
Journal:  Phys Med Biol       Date:  2000-07       Impact factor: 3.609

3.  Optimal field splitting for large intensity-modulated fields.

Authors:  Srijit Kamath; Sartaj Sahni; Sanjay Ranka; Jonathan Li; Jatinder Palta
Journal:  Med Phys       Date:  2004-12       Impact factor: 4.071

4.  Generalized field-splitting algorithms for optimal IMRT delivery efficiency.

Authors:  Srijit Kamath; Sartaj Sahni; Jonathan Li; Sanjay Ranka; Jatinder Palta
Journal:  Phys Med Biol       Date:  2007-08-31       Impact factor: 3.609

  4 in total

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