Macrotroponin causing elevation in cardiac troponin I.

We report a case of macrotroponin causing persistently raised levels of cardiac troponin I (cTnI) in a 57-year-old man with recurrent atypical chest pain. Macrotroponin, a troponin-immunoglobulin complex, should be considered when cTnI values are inconsistent with the clinical picture, and fail to demonstrate a rise and/or fall pattern in suspected cases of acute coronary syndrome. Clear and effective communication between cardiologists and laboratorians is essential in the management of patients with macrotroponin.