| Literature DB >> 24997977 |
Jian Yang1, Shi-Ling Zheng, Heng-Mu Zhang, Xiao-Ya Liu, Jing Li, Jun-Min Li, Jian-Ping Chen.
Abstract
The virus-derived small interfering RNAs (vsiRNAs) of Chinese wheat mosaic virus (CWMV), a member of the genus Furovirus, were characterised from wheat plants by deep sequencing. CWMV vsiRNAs of 21-22 nt in length predominated, suggesting that there might be a conserved mechanism of DCL2 and DCL4 involvement in the biogenesis of vsiRNAs, as well as a common RNA silencing pathway in CWMV-infected wheat plants. The 5'-terminal base of vsiRNAs was biased towards A/U, suggesting that CWMV vsiRNAs might be loaded into diverse AGO-containing RISCs to disturb the gene expression of host plants. Possible targets for some of the vsiRNAs were predicted.Entities:
Mesh：
Substances：
Year: 2014 PMID： 24997977 DOI： 10.1007/s00705-014-2155-7
Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574