Literature DB >> 24997847

Italian survey on general pediatricians' approach to children with gastroesophageal reflux symptoms.

Paolo Quitadamo1, Erasmo Miele, Angelo Alongi, Francesco Paolo Brunese, Maria Elisabetta Di Cosimo, Dante Ferrara, Silvia Gambotto, Adima Lamborghini, Maddalena Mercuri, Angela Pasinato, Renato Sansone, Concetta Vitale, Alberto Villani, Annamaria Staiano.   

Abstract

UNLABELLED: The aim of the present study was to investigate the current approach of Italian general pediatricians to children with gastroesophageal reflux (GER) symptoms, evaluating the implementation of the 2009 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN)-European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) guidelines. One hundred randomly identified Italian general pediatricians were asked to complete a case report-structured questionnaire investigating their approach to infants, children, and adolescents with symptoms suggestive of GER. Only 2 % of them showed complete adherence to the guidelines. Thirty-nine percent of them diagnosed GER disease based on clinical symptoms, irrespective of the age of the child; 56 % prescribed proton pump inhibitors (PPIs) in infants with unexplained crying and/or distressed behavior and 38 % in infants with uncomplicated recurrent regurgitation and vomiting; 57 % prescribed PPIs in children younger than 8-12 years of age with vomiting and heartburn, without specific testing; and 54 % discontinued PPI therapy abruptly. The overall rate of pediatricians over-prescribing PPIs was 79 %.
CONCLUSION: According to our findings, most Italian general pediatricians do not seem to follow the recommendations of the 2009 NASPGHAN-ESPGHAN reflux guidelines and often prescribe PPIs despite a lack of efficacy for the symptoms being treated. We are well aware that the guidelines address the average situation and that the evaluation of individual patients may frequently reveal reasons for opening criteria for exceptions. Nevertheless, the over-diagnosis of gastroesophageal reflux disease (GERD) places undue burden on both families and national health system which has not been impacted by the publication of international guidelines.

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Year:  2014        PMID: 24997847     DOI: 10.1007/s00431-014-2369-4

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  24 in total

Review 1.  Review article: long-term use of proton pump inhibitors in GORD--help or hindrance?

Authors:  G N Tytgat
Journal:  Aliment Pharmacol Ther       Date:  2001-09       Impact factor: 8.171

2.  Infants and proton pump inhibitors: tribulations, no trials.

Authors:  Susan R Orenstein; Eric Hassall
Journal:  J Pediatr Gastroenterol Nutr       Date:  2007-10       Impact factor: 2.839

3.  Are we overprescribing antireflux medications for infants with regurgitation?

Authors:  Vikram Khoshoo; Dean Edell; Aaron Thompson; Mitchell Rubin
Journal:  Pediatrics       Date:  2007-11       Impact factor: 7.124

4.  Gastric polyps and nodules in children receiving long-term omeprazole therapy.

Authors:  Dinesh S Pashankar; David M Israel
Journal:  J Pediatr Gastroenterol Nutr       Date:  2002-11       Impact factor: 2.839

5.  Characteristics of children receiving proton pump inhibitors continuously for up to 11 years duration.

Authors:  Eric Hassall; Wendy Kerr; Hashem B El-Serag
Journal:  J Pediatr       Date:  2007-03       Impact factor: 4.406

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7.  Prevalence and management of gastroesophageal reflux disease in children and adolescents: a nationwide cross-sectional observational study.

Authors:  Léonie Martigne; Pierre-Henri Delaage; Florence Thomas-Delecourt; Geneviève Bonnelye; Philippe Barthélémy; Frédéric Gottrand
Journal:  Eur J Pediatr       Date:  2012-08-18       Impact factor: 3.183

8.  Multicenter, double-blind, randomized, placebo-controlled trial assessing the efficacy and safety of proton pump inhibitor lansoprazole in infants with symptoms of gastroesophageal reflux disease.

Authors:  Susan R Orenstein; Eric Hassall; Wanda Furmaga-Jablonska; Stuart Atkinson; Marsha Raanan
Journal:  J Pediatr       Date:  2008-12-03       Impact factor: 4.406

9.  Gastroesophageal reflux in children: pathogenesis, prevalence, diagnosis, and role of proton pump inhibitors in treatment.

Authors:  Benjamin D Gold; James W Freston
Journal:  Paediatr Drugs       Date:  2002       Impact factor: 3.022

10.  Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN).

Authors:  Yvan Vandenplas; Colin D Rudolph; Carlo Di Lorenzo; Eric Hassall; Gregory Liptak; Lynnette Mazur; Judith Sondheimer; Annamaria Staiano; Michael Thomson; Gigi Veereman-Wauters; Tobias G Wenzl
Journal:  J Pediatr Gastroenterol Nutr       Date:  2009-10       Impact factor: 2.839

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4.  A large-scale study to describe the prevalence, characteristics and management of functional gastrointestinal disorders in African infants.

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