Literature DB >> 24997465

Variation in benzodiazepine and antipsychotic use in people aged 65 years and over in New Zealand.

Gary Jackson, Catherine Gerard1, Nikolai Minko, Nirasha Parsotam.   

Abstract

AIMS: To examine the variation in the dispensing of antipsychotic and benzodiazepine medicines in the elderly (aged 65+) across New Zealand.
METHODS: Data drawn from the New Zealand Pharmaceutical Collection for the New Zealand Atlas of Healthcare Variation was used to establish a regression model to examine dispensing rates by age, gender, district health board (DHB) of domicile and aged residential care usage rates over a 4 year period 2008/09 to 2011/12.
RESULTS: On average 24 per 1000 people aged 65+ in New Zealand were dispensed an antipsychotic in any given quarter. Benzodiazepine dispensing rates were even higher, at 109 per 1000 aged 65+. Both rates climbed steeply with age, were higher in females, and had a 1.6 to 1.8 fold variation across DHBs. Rates did not vary significantly with rest home and private hospital residential care usage, but antipsychotic rates appeared related to the use of psychogeriatric and dementia beds.
CONCLUSION: Given the evident harms associated with the use of antipsychotic and benzodiazepine medicines in the elderly, and the relatively poor efficacy of antipsychotics in dementia care, prescribing of these medicines should be reassessed. DHBs should examine the causes of the high rates in their area and design interventions to reduce the rates.

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Year:  2014        PMID: 24997465

Source DB:  PubMed          Journal:  N Z Med J        ISSN: 0028-8446


  5 in total

Review 1.  Deprescribing Benzodiazepines in Older Patients: Impact of Interventions Targeting Physicians, Pharmacists, and Patients.

Authors:  Brendan J Ng; David G Le Couteur; Sarah N Hilmer
Journal:  Drugs Aging       Date:  2018-06       Impact factor: 3.923

2.  Improvements in the prescribing of antipsychotics in dementia and psychogeriatric units in New Zealand.

Authors:  June M Tordoff; Nagham J Ailabouni; Dorothy P Browne; Hesham S Al-Sallami; Andrew R Gray
Journal:  Int J Clin Pharm       Date:  2016-05-30

3.  Adverse performance effects of acute lorazepam administration in elderly long-term users: pharmacokinetic and clinical predictors.

Authors:  Nunzio Pomara; Sang Han Lee; Davide Bruno; Timothy Silber; David J Greenblatt; Eva Petkova; John J Sidtis
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2014-09-06       Impact factor: 5.067

4.  Benzodiazepine and Z-Drug Use and the Risk of Developing Dementia.

Authors:  Francisco Torres-Bondia; Farida Dakterzada; Leonardo Galván; Miquel Buti; Gaston Besanson; Eric Grill; Roman Buil; Jordi de Batlle; Gerard Piñol-Ripoll
Journal:  Int J Neuropsychopharmacol       Date:  2022-04-19       Impact factor: 5.678

5.  Addressing Barriers to Reducing Prescribing and Implementing Deprescribing of Sedative-Hypnotics in Primary Care.

Authors:  Lisa Burry; Justin Turner; Timothy Morgenthaler; Cara Tannenbaum; Hyung J Cho; Evelyn Gathecha; Flora Kisuule; Abi Vijenthira; Christine Soong
Journal:  Ann Pharmacother       Date:  2021-07-23       Impact factor: 3.154

  5 in total

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