Marcel Kraft1, Karolos Fostiropoulos1, Nicolas Gürtler2, André Arnoux3, Nikolaos Davaris4, Christoph Arens4. 1. Department of Otorhinolaryngology, Head and Neck Surgery, Kantonsspital Baselland, Liestal, Switzerland. 2. Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Basel, Basel, Switzerland. 3. Department of Otorhinolaryngology, Head and Neck Surgery, Kantonsspital AG, Aarau, Switzerland. 4. Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Magdeburg, Magdeburg, Germany.
Abstract
BACKGROUND: Narrow band imaging (NBI) is a new imaging technique for the depiction of tumor-specific neoangiogenesis. The purpose of the present study was to assess the value of NBI in the early diagnosis of laryngeal cancer. METHODS: This prospective study includes 205 consecutive patients with a laryngeal lesion scheduled for microlaryngoscopy. NBI was immediately performed after white light endoscopy (WLE), whereas excisional biopsy was carried out for histologic verification of diagnosis. RESULTS: In identifying laryngeal cancer and its precursor lesions, NBI with WLE showed a significantly higher sensitivity (97% vs 79%) and accuracy (97% vs 90%) than WLE alone, but the specificity (96% vs 95%) was essentially equal in both methods. CONCLUSION: NBI qualifies for rapid detection and delineation of suspicious lesions. Additionally, this noninvasive method is also beneficial in a variety of benign lesions.
BACKGROUND: Narrow band imaging (NBI) is a new imaging technique for the depiction of tumor-specific neoangiogenesis. The purpose of the present study was to assess the value of NBI in the early diagnosis of laryngeal cancer. METHODS: This prospective study includes 205 consecutive patients with a laryngeal lesion scheduled for microlaryngoscopy. NBI was immediately performed after white light endoscopy (WLE), whereas excisional biopsy was carried out for histologic verification of diagnosis. RESULTS: In identifying laryngeal cancer and its precursor lesions, NBI with WLE showed a significantly higher sensitivity (97% vs 79%) and accuracy (97% vs 90%) than WLE alone, but the specificity (96% vs 95%) was essentially equal in both methods. CONCLUSION: NBI qualifies for rapid detection and delineation of suspicious lesions. Additionally, this noninvasive method is also beneficial in a variety of benign lesions.
Authors: Dina V Hingorani; Aaron J Lemieux; Joseph R Acevedo; Heather L Glasgow; Suraj Kedarisetty; Michael A Whitney; Alfredo A Molinolo; Roger Y Tsien; Quyen T Nguyen Journal: Oral Oncol Date: 2017-06-27 Impact factor: 5.337