Literature DB >> 24991953

Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases.

Lin Mei1, Klaus-Armin Nave2.   

Abstract

Neuregulins (NRGs) comprise a large family of growth factors that stimulate ERBB receptor tyrosine kinases. NRGs and their receptors, ERBBs, have been identified as susceptibility genes for diseases such as schizophrenia (SZ) and bipolar disorder. Recent studies have revealed complex Nrg/Erbb signaling networks that regulate the assembly of neural circuitry, myelination, neurotransmission, and synaptic plasticity. Evidence indicates there is an optimal level of NRG/ERBB signaling in the brain and deviation from it impairs brain functions. NRGs/ERBBs and downstream signaling pathways may provide therapeutic targets for specific neuropsychiatric symptoms.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24991953      PMCID： PMC4189115          DOI： 10.1016/j.neuron.2014.06.007

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  315 in total

1.  Presynaptic dopamine D(4) receptor localization in the rat nucleus accumbens shell.

Authors:  A L Svingos; S Periasamy; V M Pickel
Journal:  Synapse       Date:  2000-06-01       Impact factor: 2.562

2.  Elevated ErbB4 mRNA is related to interneuron deficit in prefrontal cortex in schizophrenia.

Authors:  Dipesh Joshi; Janice M Fullerton; Cynthia Shannon Weickert
Journal:  J Psychiatr Res       Date:  2014-03-03       Impact factor: 4.791

3.  Reversal of impaired hippocampal long-term potentiation and contextual fear memory deficits in Angelman syndrome model mice by ErbB inhibitors.

Authors:  Hanoch Kaphzan; Pepe Hernandez; Joo In Jung; Kiriana K Cowansage; Katrin Deinhardt; Moses V Chao; Ted Abel; Eric Klann
Journal:  Biol Psychiatry       Date:  2012-03-03       Impact factor: 13.382

4.  ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases.

Authors:  M A Olayioye; I Beuvink; K Horsch; J M Daly; N E Hynes
Journal:  J Biol Chem       Date:  1999-06-11       Impact factor: 5.157

5.  Immunohistochemical evidence for impaired neuregulin-1 signaling in the prefrontal cortex in schizophrenia and in unipolar depression.

Authors:  Iris Bertram; Hans-Gert Bernstein; Uwe Lendeckel; Alicja Bukowska; Henrik Dobrowolny; Gerburg Keilhoff; Dimitrios Kanakis; Christian Mawrin; Hendrik Bielau; Peter Falkai; Bernhard Bogerts
Journal:  Ann N Y Acad Sci       Date:  2007-01       Impact factor: 5.691

6.  Microarray analysis of postmortem temporal cortex from patients with schizophrenia.

Authors:  Christopher Aston; Lixin Jiang; Boris P Sokolov
Journal:  J Neurosci Res       Date:  2004-09-15       Impact factor: 4.164

7.  Neuregulin blocks synaptic strengthening after epileptiform activity in the rat hippocampus.

Authors:  Sloka S Iyengar; David D Mott
Journal:  Brain Res       Date:  2008-02-29       Impact factor: 3.252

8.  Common variants on chromosome 6p22.1 are associated with schizophrenia.

Authors:  Jianxin Shi; Douglas F Levinson; Jubao Duan; Alan R Sanders; Yonglan Zheng; Itsik Pe'er; Frank Dudbridge; Peter A Holmans; Alice S Whittemore; Bryan J Mowry; Ann Olincy; Farooq Amin; C Robert Cloninger; Jeremy M Silverman; Nancy G Buccola; William F Byerley; Donald W Black; Raymond R Crowe; Jorge R Oksenberg; Daniel B Mirel; Kenneth S Kendler; Robert Freedman; Pablo V Gejman
Journal:  Nature       Date:  2009-07-01       Impact factor: 49.962

9.  Behavioral characteristics of a nervous system-specific erbB4 knock-out mouse.

Authors:  Mari S Golub; Stacey L Germann; K C Kent Lloyd
Journal:  Behav Brain Res       Date:  2004-08-12       Impact factor: 3.332

10.  Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia.

Authors:  Nadine Norton; Valentina Moskvina; Derek W Morris; Nicholas J Bray; Stanley Zammit; Nigel M Williams; Hywel J Williams; Anna C Preece; Sarah Dwyer; Jennifer C Wilkinson; Gillian Spurlock; George Kirov; Paul Buckland; John L Waddington; Michael Gill; Aiden P Corvin; Michael J Owen; Michael C O'Donovan
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2006-01-05       Impact factor: 3.568
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  222 in total

1.  Neuregulin1β Effects on Brain Tissue via ERK5-Dependent MAPK Pathway in a Rat Model of Cerebral Ischemia-Reperfusion Injury.

Authors:  Ning Gu; Keli Ge; Cui Hao; Yaqing Ji; Hongyun Li; Yunliang Guo
Journal:  J Mol Neurosci       Date:  2017-03-06       Impact factor: 3.444

2.  The ketogenic diet increases Neuregulin 1 expression via elevating histone acetylation and its anti-seizure effect requires ErbB4 kinase activity.

Authors:  Jin Wang; Jie Huang; Shan Yao; Jia-Hui Wu; Hui-Bin Li; Feng Gao; Ying Wang; Guo-Bin Huang; Qiang-Long You; Jianhua Li; Xiaohui Chen; Xiang-Dong Sun
Journal:  Cell Biosci       Date:  2021-05-21       Impact factor: 7.133

3.  The ER structural protein Rtn4A stabilizes and enhances signaling through the receptor tyrosine kinase ErbB3.

Authors:  Jason Hatakeyama; Jessica H Wald; Hanine Rafidi; Antonio Cuevas; Colleen Sweeney; Kermit L Carraway
Journal:  Sci Signal       Date:  2016-06-28       Impact factor: 8.192

4.  Miz1 Controls Schwann Cell Proliferation via H3K36me2 Demethylase Kdm8 to Prevent Peripheral Nerve Demyelination.

Authors:  David Fuhrmann; Marco Mernberger; Andrea Nist; Thorsten Stiewe; Hans-Peter Elsässer
Journal:  J Neurosci       Date:  2017-12-07       Impact factor: 6.167

5.  A systematic meta-analysis of the association of Neuregulin 1 (NRG1), D-amino acid oxidase (DAO), and DAO activator (DAOA)/G72 polymorphisms with schizophrenia.

Authors:  Vinita Jagannath; Miriam Gerstenberg; Christoph U Correll; Susanne Walitza; Edna Grünblatt
Journal:  J Neural Transm (Vienna)       Date:  2017-09-01       Impact factor: 3.575

6.  Structural Similarities between Neuregulin 1-3 Isoforms Determine Their Subcellular Distribution and Signaling Mode in Central Neurons.

Authors:  Detlef Vullhorst; Tanveer Ahmad; Irina Karavanova; Carolyn Keating; Andres Buonanno
Journal:  J Neurosci       Date:  2017-04-21       Impact factor: 6.167

Review 7.  Electrophysiological endophenotypes in rodent models of schizophrenia and psychosis.

Authors:  Andrew M Rosen; Timothy Spellman; Joshua A Gordon
Journal:  Biol Psychiatry       Date:  2015-03-27       Impact factor: 13.382

Review 8.  Development and Functional Diversification of Cortical Interneurons.

Authors:  Lynette Lim; Da Mi; Alfredo Llorca; Oscar Marín
Journal:  Neuron       Date:  2018-10-24       Impact factor: 17.173

9.  Epigenetic meta-analysis across three civilian cohorts identifies NRG1 and HGS as blood-based biomarkers for post-traumatic stress disorder.

Authors:  Monica Uddin; Andrew Ratanatharathorn; Don Armstrong; Pei-Fen Kuan; Allison E Aiello; Evelyn J Bromet; Sandro Galea; Karestan C Koenen; Benjamin Luft; Kerry J Ressler; Derek E Wildman; Caroline M Nievergelt; Alicia Smith
Journal:  Epigenomics       Date:  2018-11-20       Impact factor: 4.778

Review 10.  The scales and tales of myelination: using zebrafish and mouse to study myelinating glia.

Authors:  Sarah D Ackerman; Kelly R Monk
Journal:  Brain Res       Date:  2015-10-20       Impact factor: 3.252
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