BACKGROUND: Cardiac magnetic resonance using the Simpson method is the gold standard for right ventricular volumetry. However, this method is time-consuming and not without sources of error. Knowledge-based reconstruction is a novel post-processing approach that reconstructs the right ventricular endocardial shape based on anatomical landmarks and a database of various right ventricular configurations. OBJECTIVE: To assess the feasibility, accuracy and labor intensity of knowledge-based reconstruction in repaired tetralogy of Fallot (TOF). MATERIALS AND METHODS: The short-axis cine cardiac MR datasets of 35 children and young adults (mean age 14.4 ± 2.5 years) after TOF repair were studied using both knowledge-based reconstruction and the Simpson method. Intraobserver, interobserver and inter-method variability were assessed using Bland-Altman analyses. RESULTS: Knowledge-based reconstruction was feasible and highly accurate as compared to the Simpson method. Intra- and inter-method variability for knowledge-based reconstruction measurements showed good agreement. Volumetric assessment using knowledge-based reconstruction was faster when compared with the Simpson method (10.9 ± 2.0 vs. 7.1 ± 2.4 min, P < 0.001). CONCLUSION: In patients with repaired tetralogy of Fallot, knowledge-based reconstruction is a feasible, accurate and reproducible method for measuring right ventricular volumes and ejection fraction. The post-processing time of right ventricular volumetry using knowledge-based reconstruction was significantly shorter when compared with the routine Simpson method.
BACKGROUND: Cardiac magnetic resonance using the Simpson method is the gold standard for right ventricular volumetry. However, this method is time-consuming and not without sources of error. Knowledge-based reconstruction is a novel post-processing approach that reconstructs the right ventricular endocardial shape based on anatomical landmarks and a database of various right ventricular configurations. OBJECTIVE: To assess the feasibility, accuracy and labor intensity of knowledge-based reconstruction in repaired tetralogy of Fallot (TOF). MATERIALS AND METHODS: The short-axis cine cardiac MR datasets of 35 children and young adults (mean age 14.4 ± 2.5 years) after TOF repair were studied using both knowledge-based reconstruction and the Simpson method. Intraobserver, interobserver and inter-method variability were assessed using Bland-Altman analyses. RESULTS: Knowledge-based reconstruction was feasible and highly accurate as compared to the Simpson method. Intra- and inter-method variability for knowledge-based reconstruction measurements showed good agreement. Volumetric assessment using knowledge-based reconstruction was faster when compared with the Simpson method (10.9 ± 2.0 vs. 7.1 ± 2.4 min, P < 0.001). CONCLUSION: In patients with repaired tetralogy of Fallot, knowledge-based reconstruction is a feasible, accurate and reproducible method for measuring right ventricular volumes and ejection fraction. The post-processing time of right ventricular volumetry using knowledge-based reconstruction was significantly shorter when compared with the routine Simpson method.
Authors: Teresa Moroseos; Lee Mitsumori; William S Kerwin; David J Sahn; Willem A Helbing; Philip J Kilner; Alan Shurman; Harold Litt; Florence H Sheehan Journal: Am J Cardiol Date: 2010-04-21 Impact factor: 2.778
Authors: Whal Lee; Shi-Joon Yoo; Susan L Roche; Paul Kantor; Glen van Arsdell; Eun-Ah Park; Andrew Redington; Lars Grosse-Wortmann Journal: Int J Cardiol Date: 2012-04-25 Impact factor: 4.164
Authors: Kathleen Gilbert; Nickolas Forsch; Sanjeet Hegde; Charlene Mauger; Jeffrey H Omens; James C Perry; Beau Pontré; Avan Suinesiaputra; Alistair A Young; Andrew D McCulloch Journal: J Cardiovasc Transl Res Date: 2018-01-02 Impact factor: 4.132