Literature DB >> 24985330

Protein homeostasis at the plasma membrane.

Pirjo M Apaja1, Gergely L Lukacs2.   

Abstract

The plasma membrane (PM) and endocytic protein quality control (QC) in conjunction with the endosomal sorting machinery either repairs or targets conformationally damaged membrane proteins for lysosomal/vacuolar degradation. Here, we provide an overview of emerging aspects of the underlying mechanisms of PM QC that fulfill a critical role in preserving cellular protein homeostasis in health and diseases. ©2014 Int. Union Physiol. Sci./Am. Physiol. Soc.

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Year:  2014        PMID: 24985330      PMCID: PMC4103059          DOI: 10.1152/physiol.00058.2013

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN: 1548-9221


  154 in total

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2.  Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation.

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3.  Insights into MLC pathogenesis: GlialCAM is an MLC1 chaperone required for proper activation of volume-regulated anion currents.

Authors:  Xavier Capdevila-Nortes; Tania López-Hernández; Pirjo M Apaja; Miguel López de Heredia; Sònia Sirisi; Gerard Callejo; Tanit Arnedo; Virginia Nunes; Gergely L Lukacs; Xavier Gasull; Raúl Estévez
Journal:  Hum Mol Genet       Date:  2013-06-20       Impact factor: 6.150

4.  c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity.

Authors:  Eiji Goto; Satoshi Ishido; Yuya Sato; Shinji Ohgimoto; Kaori Ohgimoto; Motoko Nagano-Fujii; Hak Hotta
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5.  Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules.

Authors:  Lidia M Duncan; Siân Piper; Roger B Dodd; Mark K Saville; Chris M Sanderson; J Paul Luzio; Paul J Lehner
Journal:  EMBO J       Date:  2006-04-06       Impact factor: 11.598

6.  VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo.

Authors:  Xuefeng Ren; James H Hurley
Journal:  EMBO J       Date:  2010-02-11       Impact factor: 11.598

7.  ALIX is a Lys63-specific polyubiquitin binding protein that functions in retrovirus budding.

Authors:  Dara P Dowlatshahi; Virginie Sandrin; Sandro Vivona; Thomas A Shaler; Stephen E Kaiser; Francesco Melandri; Wesley I Sundquist; Ron R Kopito
Journal:  Dev Cell       Date:  2012-11-29       Impact factor: 12.270

8.  MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation.

Authors:  Aude De Gassart; Voahirana Camosseto; Jacques Thibodeau; Maurizio Ceppi; Nadia Catalan; Philippe Pierre; Evelina Gatti
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-27       Impact factor: 11.205

9.  Mechanism-based corrector combination restores ΔF508-CFTR folding and function.

Authors:  Tsukasa Okiyoneda; Guido Veit; Johanna F Dekkers; Miklos Bagdany; Naoto Soya; Haijin Xu; Ariel Roldan; Alan S Verkman; Mark Kurth; Agnes Simon; Tamas Hegedus; Jeffrey M Beekman; Gergely L Lukacs
Journal:  Nat Chem Biol       Date:  2013-05-12       Impact factor: 15.040

10.  N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic.

Authors:  Rina Glozman; Tsukasa Okiyoneda; Cory M Mulvihill; James M Rini; Herve Barriere; Gergely L Lukacs
Journal:  J Cell Biol       Date:  2009-03-23       Impact factor: 10.539

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  18 in total

1.  The endosomal trafficking factors CORVET and ESCRT suppress plasma membrane residence of the renal outer medullary potassium channel (ROMK).

Authors:  Timothy D Mackie; Bo-Young Kim; Arohan R Subramanya; Daniel J Bain; Allyson F O'Donnell; Paul A Welling; Jeffrey L Brodsky
Journal:  J Biol Chem       Date:  2018-01-08       Impact factor: 5.157

2.  Nonsteroidal Anti-inflammatory Drugs Potently Inhibit the Replication of Zika Viruses by Inducing the Degradation of AXL.

Authors:  Ting Pan; Zhilin Peng; Likai Tan; Fan Zou; Nan Zhou; Bingfeng Liu; Liting Liang; Cancan Chen; Jun Liu; Liyang Wu; Guangyan Liu; Zhiqin Peng; Weiwei Liu; Xiancai Ma; Junsong Zhang; Xun Zhu; Ting Liu; Mengfeng Li; Xi Huang; Liang Tao; Yiwen Zhang; Hui Zhang
Journal:  J Virol       Date:  2018-09-26       Impact factor: 5.103

3.  Proteostasis: Chaperoning for hearing loss.

Authors:  Gergely L Lukacs
Journal:  Nat Chem Biol       Date:  2016-05-18       Impact factor: 15.040

Review 4.  Pharmacoperones as Novel Therapeutics for Diverse Protein Conformational Diseases.

Authors:  Ya-Xiong Tao; P Michael Conn
Journal:  Physiol Rev       Date:  2018-04-01       Impact factor: 37.312

Review 5.  CFTR: A New Horizon in the Pathomechanism and Treatment of Pancreatitis.

Authors:  Péter Hegyi; Michael Wilschanski; Shmuel Muallem; Gergely L Lukacs; Miklós Sahin-Tóth; Aliye Uc; Michael A Gray; Zoltán Rakonczay; József Maléth
Journal:  Rev Physiol Biochem Pharmacol       Date:  2016       Impact factor: 5.545

6.  Measuring Plasma Membrane Recycling Using Microscopic and Biochemical Approaches.

Authors:  Priyanka Sharma; Sameena Parveen; Sunando Datta
Journal:  Methods Mol Biol       Date:  2022

7.  CHIP Regulates Aquaporin-2 Quality Control and Body Water Homeostasis.

Authors:  Qi Wu; Hanne B Moeller; Donté A Stevens; Rebekah Sanchez-Hodge; Gabrielle Childers; Marleen L A Kortenoeven; Lei Cheng; Lena L Rosenbaek; Carrie Rubel; Cam Patterson; Trairak Pisitkun; Jonathan C Schisler; Robert A Fenton
Journal:  J Am Soc Nephrol       Date:  2017-12-14       Impact factor: 10.121

8.  A Temperature-Sensitive Misfolded bri1-301 Receptor Requires Its Kinase Activity to Promote Growth.

Authors:  Xiawei Zhang; Linyao Zhou; Yukuo Qin; Yongwu Chen; Xiaolei Liu; Muyang Wang; Juan Mao; Jianjun Zhang; Zuhua He; Linchuan Liu; Jianming Li
Journal:  Plant Physiol       Date:  2018-10-17       Impact factor: 8.340

9.  Leveraging the withered tail tip phenotype in C. elegans to identify proteins that influence membrane properties.

Authors:  Emma Svensk; Jana Biermann; Sofia Hammarsten; Fredrik Magnusson; Marc Pilon
Journal:  Worm       Date:  2016-06-28

10.  Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell.

Authors:  Miklos Bagdany; Guido Veit; Ryosuke Fukuda; Radu G Avramescu; Tsukasa Okiyoneda; Imad Baaklini; Jay Singh; Guy Sovak; Haijin Xu; Pirjo M Apaja; Sara Sattin; Lenore K Beitel; Ariel Roldan; Giorgio Colombo; William Balch; Jason C Young; Gergely L Lukacs
Journal:  Nat Commun       Date:  2017-08-30       Impact factor: 14.919

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