We describe a new class of charge inverted zwitterionic sulfated lipids (AS) with a cationic quaternary amine anchored at the membrane interface and an anionic sulfate moiety extended into the aqueous phase. These lipids have exceptionally high transition temperatures and assemble into lipid aggregates when dispersed in aqueous solutions.
We describe a new class of charge pan class="Chemical">invertedzwitterionic sulfatedlipids (AS) with a cationic quaternary amine anchored at the membrane interface and an anionic sulfate moiety extended into the aqueous phase. These lipids have exceptionally high transition temperatures and assemble into lipid aggregates when dispersed in aqueous solutions.
Authors: Aditya G Kohli; Paul H Kierstead; Vincent J Venditto; Colin L Walsh; Francis C Szoka Journal: J Control Release Date: 2014-05-06 Impact factor: 9.776
Authors: Jason B Miller; Shuyuan Zhang; Petra Kos; Hu Xiong; Kejin Zhou; Sofya S Perelman; Hao Zhu; Daniel J Siegwart Journal: Angew Chem Int Ed Engl Date: 2016-12-16 Impact factor: 15.336